 | | Vol. 15.00 – 5 January, 2023 |
| |
|
|
| Scientists reported that the large fluctuations in cell density that accompany unjamming resulted in repeated mechanical deformations of cells and nuclei.
[Nature Materials] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Investigators reported that ataxia telangiectasia mutated (ATM) controlled the early transcriptional response to estrogens. This response depended on topoisomerase II (TOP2), which generated TOP2-DNA double-strand break complexes and rejoined the breaks.
[Cell Reports] |
|
|
|
| Researchers reported that the ubiquitin E3 ligase HERC3 could promote YAP/TAZ activation independently of its enzymatic activity. HERC3 directly bound to β-TrCP and prevented YAP/TAZ ubiquitination and degradation.
[EMBO Journal] |
|
|
|
| In vitro studies, including assays for colony formation, cell viability, and relative cell fitness, were employed to identify effects of PAQR8 on breast cancer dormancy or recurrence in the context of therapy.
[Breast Cancer Research] |
|
|
|
| Investigators evaluated the expression level of miR-1275 in plasma samples and its biological functions in the chemoresistance of breast cancer. The expression levels of miR-1275 in plasma samples and cells were measured by RT-qPCR.
[International Journal Of Biological Sciences] |
|
|
|
| Researchers found enhanced p-N-Myc downstream regulated gene 1 (NDRG1) by transforming growth factor β 1 and explored whether it drove NDRG1 pleiotropy and TNBC progression.
[International Journal Of Biological Sciences] |
|
|
|
| Scientists demonstrated that elastin-like recombinamer hydrogels could be suitable biomaterials to develop breast cancer models.
[Biomacromolecules] |
|
|
|
| Investigators characterized BCSCs through the genetic profiling of different BCSCs phenotypic subsets to determine their related genetic pathways.
[Cancer Cell International] |
|
|
|
| Bone metastatic breast cancer SCP2 cells were induced for sclerostin SOST silencing or overexpression and their bone metastatic behaviors were tested in vitro and in vivo.
[Molecular Cancer] |
|
|
|
| To test whether transmembrane (TMEM) 9A protein might promote breast cancer progression, researchers performed a series of loss/gain-of-function experiments and found that breast cancer cells with TMEM9A deletion inhibited cell proliferation, migration, and invasion along with induced apoptosis.
[Biological & Pharmaceutical Bulletin] |
|  |
|
|
|
| The authors summarize all of the reported long non-coding RNAs involved in cell cycle regulation in breast cancer.
[Biological Research] |
|
|
|
| Scientists revisit the studies on proteoglycan (PG) characterization in breast cancer using LC-MS/MS based proteomics approach, which will be further helpful for the identification of potential PGs-based biomarkers or therapeutic targets.
[Proteomics Clinical Applications] |
|
|
|
|
| Gilead Sciences, Inc. announced that the European Medicines Agency has validated a Type II variation Marketing Authorization Application for Trodelvy® for the treatment of adult patients with HR+/HER2– metastatic breast cancer.
[Gilead Sciences, Inc.] |
|
|
|
| UBC faculty of medicine’s Drs. Allen Eaves and Paula Gordon were among the UBC community members who have been appointed to the Order of Canada.
[UBC Faculty of Medicine] |
|
|
|
|
| January 24 – 26, 2023
Boston, Massachusetts, United States |
|
|
|
|
|
| | Toulouse Cancer Research Center – Toulouse, France |
|
|
|
| | University Medical Center Freiburg – Freiburg, Germany |
|
|
|
| | Institute of Cancer Research – London, England, United Kingdom |
|
|
|
| | UTHSC-Houston – Houston, Texas, United States |
|
|
|
| | UC Davis School of Medicine – Davis, California, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
