 | | Vol. 15.05 – 9 February, 2023 |
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| Researchers combined state-of-the-art data acquisition platforms and bioinformatics tools to devise PAMAF, a workflow that simultaneously examined twelve omics modalities.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors found overexpression of CCN3 in TNBC patients and identified that CCN3 knockdown diminished cancer stem cell formation, metastasis, and tumor growth in vitro and in vivo.
[Cell Death & Disease] |
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| Scientists found that the expression of TMEM105 associated with glycolysis was dramatically elevated from normal to breast cancer to breast cancer liver metastasis tissues.
[Cell Death & Disease] |
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| Investigators explored the regulatory roles of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) in methyltransferase-like 3 (METTL3) stability and N6-methyladenosine (m6A) modification of mRNA.
[Oncogene] |
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| Wild-type ERα-positive MCF7 and ERα-negative MDA-MB-231 breast cancer cells and their tamoxifen-resistant counterparts were analyzed for cellular metabolism using the Seahorse metabolic analyzer.
[Cancer & Metabolism] |
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| Researchers reported gold nanotriangles tuned with anionic and cationic surface charge conjugating triphenylphosphonium targeting breast cancer cells with 5-aminoleuvinic acid based photodynamic therapy, in vitro.
[Scientific Reports] |
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| Scientists analyzed the effects and mechanisms of isopimaric acid on the proliferation and metastasis of breast cancer cells by cell functional assay, flow cytometry, western blot, proteomics, and other techniques in vitro and in vivo.
[Toxicology and Applied Pharmacology] |
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| The authors investigated the role and mechanism of hsa_circ_0001925 in TNBC progression. Hsa_circ_0001925, microRNA (miR)-1299, and Yin Yang 1 (YY1) levels were examined in TNBC via reverse transcription-quantitative polymerase chain reaction and western blot.
[Thoracic Cancer] |
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| Investigators demonstrated the association of Y-box binding protein 1 (YBX1) with oncogenic SET-binding factor 2 antisense RNA 1 (SBF2-AS1) via PI3K/AKT/mTOR signaling to regulate breast cancer cell proliferation.
[Molecular Biology Reports] |
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| Scientists summarize the functions of RNA-binding proteins and highlight their tremendously important roles in regulating therapy sensitivity and resistance.
[Cell Death Discovery] |
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| University of Washington (UW) Carbone Cancer Center was one of three research institutions in the United States participating in a breast cancer vaccine clinical trial and was the first to administer the vaccine to a participating patient.
[UW Carbone Cancer] |
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| February 22 – 23, 2023
Boston, Massachusetts, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Duke University – Durham, North Carolina, United States |
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| | King’s College London – London, England, United Kingdom |
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| | Vanderbilt-Ingram Cancer Center – Nashville, Tennessee, United States |
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| | University of Mississippi Medical Center – Jackson, Mississippi, United States |
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Cancer Stem Cell News
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