 | | Vol. 15.07 – 23 February, 2023 |
| |
|
|
| Scientists revealed that ZEB1-induced MIR497HG depletion contributed to breast cancer progression and tamoxifen resistance through PI3K-AKT signaling.
[Advanced Science] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| CRISPR/Cas9-based kinome screening was used to identify the copper transporter 1 (CTR1) upstream kinases. Immunofluorescence assays were utilized to detect CTR1 localization. In vitro kinase assays and mass spectrometry were performed to detect CTR1 phosphorylation.
[British Journal of Cancer] |
|
|
|
| Researchers investigated the mechanism underlying this enhanced reliance on mitochondrial metabolism of residual TNBC cells surviving neoadjuvant chemotherapy.
[Oncogene] |
|
|
|
| Investigators showed that Dicer expression correlated with metastasis and invasion without affecting cell stability in breast cancer cells.
[Journal of Cellular Physiology] |
|
|
|
| Scientists investigated the effect of differentiation-inducing factor-1 (DIF-1) on the tumor microenvironment using mouse TNBC 4T1-GFP cells, mouse macrophage RAW 264.7 cells, and mouse primary dermal fibroblasts.
[International Immunopharmacology] |
|
|
|
| The underlying mechanism leading to the development of acquired radioresistance in the EMT6 mouse mammary carcinoma cell line and the potential pathway involved was investigated by comparing differential gene expressions between parental and acquired radioresistance cells.
[Scientific Reports] |
|
|
|
| Investigators assessed the potential cytotoxicity of P. niruri extracts (and fractions) alone and in combination with doxorubicin against naïve, MCF-7, and doxorubicin-resistant breast cancer cell lines, MCF-7ADR.
[Scientific Reports] |
|
|
|
| To determine whether bufalin (BUF) could reverse the drug resistance to docetaxel and restore efficacy in breast cancer, the reversal index of BUF was detected by cell counting kit-8 assays. The effects of BUF on enhancing the apoptosis of docetaxel were detected by flow cytometry and Western blot.
[Heliyon] |
|
|
|
| To test whether stiffness-mediated alternative splicing could regulate the expression of focal adhesion kinase (FAK) splice variants and influence tumor progression, researchers first investigated FAK mRNA splicing as a function of matrix stiffness using RNAseq.
[Biophysical Journal] |
|
|
|
|
| The authors discuss genetic studies in breast cancer and central nervous system (CNS) metastases and the role of liquid biopsies in cerebrospinal fluid (CSF).
[Journal of Neuro-Oncology] |
|
|
|
|
| Atossa Therapeutics, Inc. announced that the first patient has been dosed in the Phase II EVANGELINE study. EVANGELINE is a randomized trial of (Z)-Endoxifen in premenopausal women with Estrogen Receptor positive (ER+) / Human Epidermal Growth Factor Receptor 2 negative (HER2-) breast cancer.
[Atossa Therapeutics, Inc.] |
|
|
|
|
| April 14 – 19, 2023
Orlando, Florida, United States |
|
|
|
|
|
| | Penn Medicine – Philadelphia, Pennsylvania, United States |
|
|
|
| | Institute of Cancer Research – London, England, United Kingdom |
|
|
|
| | University of Texas Health Science Center – San Antonio, Texas, United States |
|
|
|
| | Duke University – Durham, North Carolina, United States |
|
|
|
| | Vanderbilt-Ingram Cancer Center – Nashville, Tennessee, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
