 | | Vol. 15.11 – 23 March, 2023 |
| |
|
|
| Researchers evaluated the impact of the concurrent combination of talazoparib and carboplatin on cell survival in 13 TNBC cell lines. They compared the concurrent and sequential combination upon fork replication, migration, and invasion.
[British Journal of Cancer] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The Cancer Genome Atlas dataset was used to assess the expression of WAVE3 and β-catenin in breast cancer tumors. Kaplan–Meier Plotter analysis was used to correlate expression of WAVE3 and β-catenin with breast cancer patients’ survival probability.
[Breast Cancer Research] |
|
|
|
| To understand the role of metabolic pathways in in cancer cell survival and proliferation, investigators targeted glycolysis, pentose phosphate pathway, and mitochondria using three different inhibitors: 2-deoxyglucose, 6-aminonicotinamide, and doxycycline, separately and in combination.
[Biomedicine & Pharmacotherapy] |
|
|
|
| Scientists developed an integrated method to identify individual cells with differences in extracellular vesicle (EV) secretion and performed linked single-cell RNA-sequencing on cloned single cells from the metastatic breast cancer cells.
[iScience] |
|
|
|
| Researchers performed RNA sequencing, and the results revealed an increase in the expression level of novel lncRNA ENST00000370438 in tissues of patients with breast cancer (BC). qRT-PCR results showed an increase in lncRNA ENST00000370438 expression level in 23 pairs of BC tissues.
[Molecular Carcinogenesis] |
|
|
|
| The authors showed that human mammary adipocytes (M-Ads) died within 2–3 days by necrosis when grown in 2D. As an alternative, M-Ads were grown in a fibrin matrix, a 3D model that preserved their distribution, integrity, and metabolic function for up to 5 days at physiological glucose concentrations.
[Scientific Reports] |
|
|
|
| The chlorogenic acid content in Taraxacum officinale was determined by HPLC. Bovine mammary epithelial cells were infected with lipoteichoic acid to induce the mastitis model.
[PLOS One] |
|
|
|
| Small RNA interference system was employed to decrease DOC-2/DAB2 interactive protein (DAB2IP) expression in two breast cancer cell lines, MDA-MB-231 and 4T1. Cells in response to IR or antineoplastics were detected by clone formation assay or MTT method, respectively.
[International Journal of Radiation Biology] |
|
|
|
| The expression levels of circHMCU, miR-4458, and phosphoglycerate kinase 1 (PGK1) were measured by qRT-PCR or western blot. The glucose uptake, lactate production, and ATP level were assayed by related commercial kits.
[Hereditas] |
|
|
|
|
| The current definition of oligometastatic seems incomplete since it is based only on imaging findings and does not include biological features, and the majority of relevant data supporting this strategy comes from retrospective or non-randomized studies.
[Therapeutic Advances in Medical Oncology] |
|
|
|
|
| First Lady Casey DeSantis announced that Florida will be the first state in the US to collect cancer recurrence data – the Cancer Connect Collaborative’s first action to remove data access barriers for easy and timely research.
[Florida Government] |
|
|
|
|
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
|
|
|
| | Columbia University – New York City, New York, United States |
|
|
|
| | Harvard Medical School – Boston, Massachusetts, United States |
|
|
|
| | University of Alberta – Edmonton, Alberta, Canada |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
