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| The antitumor effect of VG161 and paclitaxel was confirmed in a breast cancer xenograft mouse model. [Journal of Medical Virology] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Using TNBC as a model, researchers demonstrated that aNRP2-10 could be used to isolate cancer stem cells (CSCs) from heterogeneous tumor populations and inhibit CSC function and epithelial-to-mesenchymal transition. [Science Translational Medicine] |
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| Using cancer cell lines and patient-derived tumor organoids, scientists demonstrated that loss of the negative elongation factor (NELF) complex inhibited breast cancer development through downregulating epithelial-mesenchymal transition and stemness-associated genes. [Nature Communications] |
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| Investigators showed that mammary resident macrophages regulated mammary epithelium cell division and mammary development through TNF-α-Cdk1/Cyclin B1 axis. [npj Regenerative Medicine] |
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| The authors developed a quantitative cell culture assay that modeled intercalation into epithelial monolayers. They found that tight junction proteins played a key role in this process. [Developmental Cell] |
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| Researchers identified that acetyl-CoA acyltransferase 1 (ACAA1) was highly expressed in the luminal androgen receptor (LAR) subtype of TNBC compared with adjacent normal tissues in their TNBC proteomics dataset. [Cancer Research] |
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| Scientists showed that the breast tumor suppressor gene Singleminded-2 (SIM2) promoted mitochondrial oxidative phosphorylation using breast cancer cell line models. [Experimental & Molecular Medicine] |
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| Investigators explored the anti-oxidant and anti-inflammatory effects and potential molecular mechanisms of sulforaphane in lipopolysaccharide-induced primary goat mammary epithelial cells and a mouse model of mastitis. [Journal Of Animal Science And Biotechnology] |
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| Researchers evaluated the in vitro cytotoxic effect of Haloferax mediterranei bacterioruberin-rich carotenoid extracts in six breast cancer cell lines, representative of the intrinsic phenotypes and a healthy mammary epithelium cell line. [Scientific Reports] |
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| Circ_0001387, miR-136-5p, and spindle and kinetochore-associated protein 2 (SKA2) levels were analyzed by quantitative real-time polymerase chain reaction. [Thoracic Cancer] |
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| Scientists investigated for the first time how MYC affected the biological functions of normal breast cells cocultured with exosomes derived from MYC-expression manipulated breast cancer cells. [Chemical Biology & Drug Design] |
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| Several issues, that is, high cost, toxicity, allergic reactions, less efficacy, multidrug resistance, and the economic cost of conventional anti-cancer therapies, have prompted scientists to discover innovative approaches and new chemo-preventive agents. [Cancer Medicine] |
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| NHS Grampian’s breast cancer research team is to receive the National Institute for Health Research’s CREST Award. The accolade recognizes the surgical team that has made the greatest contribution to clinical trials research across the UK during the last year. [NHS Grampian] |
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| June 3 – 7, 2023 San Diego, California, United States |
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| University of Pennsylvania – Philadelphia, Pennsylvania, United States |
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| University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| Harvard T.H. Chan School of Public Health – Boston, Massachusetts, United States |
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| Wake Forest University – Winston Salem, North Carolina, United States |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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