 | | Vol. 15.29 – 27 July, 2023 |
| |
|
|
| Using phylogenetic analyses of multiple microdissected samples from both cancer and non-cancer lesions, investigators showed unique evolutionary histories of breast cancers harboring der(1;16), a common driver alteration found in roughly 20% of breast cancers.
[Nature] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers identified several genomic alterations that were differentially prevalent in overweight or obese patients compared to lean patients and reported evidence supporting an aging accelerating effect of obesity at the genetic level.
[Nature Communications] |
|
|
|
| The authors identified novel functional roles of heat shock protein beta-1 (HSPB1), regulating chemoresistance and ferroptotic cell death in breast cancer.
[Cell Death & Disease] |
|
|
|
| Exosomal circRNA profiling of breast cancer-derived cancer-associated fibroblasts (CAFs) and normal fibroblasts was detected by high-throughput sequencing, and upregulated circTBPL1 expression was identified in CAF exosomes.
[Cell Death & Disease] |
|
|
|
| Investigators demonstrated that signal-induced proliferation-associated 1 (SIPA1), known as a Rap-GTPase-activating protein, bound DNA and served as a transcription factor.
[Oncogene] |
|
|
|
| Researchers identified a small molecule NSC260594 from the National Cancer Institute diversity set IV compound library. NSC260594 exhibited dramatic cytotoxicity in multiple TNBCs in a dose-and time-dependent manner.
[Scientific Reports] |
|
|
|
| Scientists investigated the impact of Tn antigen expression on breast cancer metastasis and its underlying mechanisms. The expression of Tn antigen was induced in two breast cancer cell lines by deleting T-synthase or Cosmc.
[Cell Biology International] |
|
|
|
| Investigators determined circulating tumor cells (CTCs) in 156 patients, who had breast cancer with a disease course of two or more years. They also measured the expression of connexin 43 in the CTCs.
[Heliyon] |
|
|
|
| Using a chicken chorioallantoic membrane model, the authors cultured MDA-MB-231 cells and treated them with dihydroartemisinin.
[Fundamental & Clinical Pharmacology] |
|  |
|
|
|
| Recent development and approval of next-generation estrogen receptor-α (ER) antagonists to target ESR1-mutant breast cancer underscores the clinical importance of this evolvability and sets a new paradigm for the treatment of ER+ breast cancers.
[Nature Reviews Cancer] |
|
|
|
|
| Five rising junior investigators were awarded a total of $1.32 million from Alabama State University’s (ASU) Cancer Biology Research and Training program to build cancer research capacity at ASU.
[Alabama State University] |
|
|
|
|
| October 16 – 19, 2023
Hong Kong |
|
|
|
|
|
| | City of Hope – Duarte, California, United States |
|
|
|
| | NICHD – Bethesda, Maryland, United States |
|
|
|
| | Albert Einstein College of Medicine – New York City, New York, United States |
|
|
|
| | NCI Center for Cancer Research – Bethesda, Maryland, United States |
|
|
|
| | Ume̴ University РUme̴, Sweden |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
