| Vol. 15.35 – 7 September, 2023 |
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| Scientists investigated the role of Jumonji and the AT-rich interaction domain-containing 2 (JARID2), a JmjC family protein, in breast cancer, as well as its latent association with obesity. [Cancer Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers found that the prolyl hydroxylase EglN1 accumulated on mitochondria under hypoxia. EglN1 substrate-binding region in the β2β3 loop was responsible for its mitochondrial translocation and contributed to breast tumor growth. [EMBO Journal] |
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| The authors highlighted that YOD1 functioned as an oncogene in TNBC via binding to CDK1 and mediated its stability and oncogenic activity. [Journal of Experimental & Clinical Cancer Research] |
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| Investigators found that ERCC Exception Repair 6 Like (ERCC6L) was highly expressed in breast cancer, especially in TNBC, which was closely related to poor outcomes of patients. [Journal of Experimental & Clinical Cancer Research] |
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| Scientists cultured circulating tumor cell-like DU4475 TNBC cells in mechanically tunable 3D fibrin hydrogel scaffolds. Mechanically tunable fibrin gels revealed specific matrix-based regulation of TNBC cell phenotype. [Advanced Healthcare Materials] |
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| Researchers studied the therapeutic potential of cantharidin for TNBC treatment by targeting epidermal growth factor receptor (EGFR), and expound its novel regulator miR-607. [Journal of Translational Medicine] |
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| Investigators discerned the biological differences between normal fibroblasts and cancer-associated fibroblasts in breast cancer and explored the underlying mechanism. [Heliyon] |
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| Scientists examined the combined treatment effects of quercetin and sodium butyrate in hormone-sensitive breast cancer cells in vitro. [Journal Of Toxicology And Environmental Health-Part A-Current Issues] |
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| Researchers investigated the anti-tumor effect of matrine on the proliferation and apoptosis of TNBC cells based on HN1 regulation in vitro and in vivo. [Chemical Biology & Drug Design] |
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| Scientists focus on F-box and WD repeat domain-containing 7 (FBXW7)’s role in a range of breast cancer malignant behaviors and summarize the pertinent cellular targets, signaling pathways, as well as the mechanisms regulating FBXW7 expression. [Journal of Experimental & Clinical Cancer Research] |
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| The authors investigate the potential of free nanoparticles in the induction or inhibition of autophagy and consider this effect on the therapy process in breast carcinoma. [Cell Biology International] |
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| The UK government announced that it will rejoin the European Union’s €95 billion research funding program known as Horizon Europe. [ScienceInsider] |
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| October 12 – 13, 2023 Singapore & Virtual |
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| University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| The George Washington University – Washington D.C., United States |
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| University of Cologne – Cologne, Germany |
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| Cedars-Sinai – Los Angeles, California, United States |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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