 | | Vol. 15.45 – 16 November, 2023 |
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| The authors integrated proteomics, transcriptomics, epigenomics, chromatin accessibility, and functional assays from human and syngeneic mouse breast cancer models to show that MAF directly interacts with estrogen receptor alpha (ERα).
[Nature Cell Biology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| To decipher the cellular plasticity that fuels phenotypic heterogeneity, scientists undertook single-cell transcriptomics analysis in TNBC to identify subpopulations in cancer stem cells.
[Journal Of Clinical Investigation] |
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| In a well-established breast cancer stem cells model, investigators identified that pharmacological inhibition of the mechanistic target of rapamycin (mTOR), suppressed Salinomycin-induced ferroptosis.
[Cell Death & Disease] |
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| Scientists found that the mineralized invasive breast cancer cells not only increased their proliferation and migration, but also showed the characteristic of doxorubicin resistance.
[npj Breast Cancer] |
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| Researchers found that ΔA146Ply suppressed the migration and invasion of TNBC cells by activating mannose receptor and toll-like receptor 4.
[Virulence] |
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| Scientists reported, for the first time, the expression profile of the Orai family members, Orai1-3, and different TRPC channels, TRPC1, 3, and 6, in breast cancer stem cells.
[Scientific Reports] |
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| Researchers investigated the expression, cis, and trans-regulatory effects, and function of a predicted HER2-associated enhancer, Her2-Enhancer1.
[Scientific Reports] |
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| Scientists used bioinformatics approaches to reveal that GREB1L was highly expressed in breast cancer tissues compared with normal breast tissues and that its upregulation was associated with a good prognosis.
[European Journal of Medical Research] |
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| By comparing the gene expression profiles of mutant p53 (mutp53) and mutp53 silenced cohorts, investigators found that FOS-related antigen-1 (FRA-1) was a potential effector of mutp53-mediated metastasis.
[FEBS Letters] |
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| The authors summarize the current research progress and clinical implementation of BRCA and BRCAness in targeted treatments for the DNA repair pathway.
[Biomedicine & Pharmacotherapy] |
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| Julie Palmer, ScD, co-director of the Boston University-Boston Medical Center Cancer Center, has been awarded a one-year, $589,000 Research Grant from the Breast Cancer Research Foundation for her research, “Breast Cancer Drivers in Black Women: Society to Cells.”
[Boston University] |
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| Article-processing charges levied by publishers on authors have become an integral — and sometimes unpopular — part of the open-access revolution. Other options are being explored.
[Nature] |
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| December 16 – 20, 2023
Waikoloa Beach, Hawaii, United States |
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| | NIH National Cancer Institute – Bethesda, Maryland, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | German Cancer Research Center in the Helmholtz Association – Heideland, Germany |
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| | China Pharmaceutical University – Nanjing, Jiangsu, China |
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| | Baylor College of Medicine – Houston, Texas, United States |
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Cancer Stem Cell News
Cell Therapy News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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