 | | Vol. 15.47 – 30 November, 2023 |
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| The authors identified key deubiquitinases that significantly impact breast cancer progression and have important implications for breast cancer therapeutics.
[Oncogene] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers demonstrated that the expression of Sine oculis homeobox homolog 1 (SIX1) varied among different subtypes of breast cancer and that it upregulated breast cancer grading and lymph node metastasis.
[Journal of Translational Medicine] |
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| Scientists highlighted patatin-like phospholipase domain-containing lipase 8 (PNPLA8) as key regulator of phospholipid metabolic reprogramming and malignant phenotypes in TNBC.
[Breast Cancer Research] |
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| Investigators synthesized the gold nanoparticles (GNPs) using a dual extract of tulsi and Vinca for breast cancer tumor regression. The GNPs were synthesized and characterized for their microscopic, spectroscopic, and crystalline properties.
[Nanomedicine] |
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| Scientists determined chromatin folding and composition over several hundred kb around estrogen-responsive genes in human breast cancer cell lines after hormone stimulation.
[Life Science Alliance] |
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| RNA sequencing found that 1-benzylimidazole held a preferable correlation with breast cancer and suppressed the expression of CSC makers.
[Environmental Toxicology] |
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| Scientists revealed a mechanism by which WASF3 overexpression affected the expression of circRNAs hsa-circ-0100153, promoting breast cancer progression by sponging hsa-miR-31/hsa-miR-767-3p/hsa-miR-935.
[Heliyon] |
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| Researchers determined the use of pharmacological lactate dehydrogenase (LDH) inhibitors to reduce aggressive behavior of breast cancer cells. The effect of LDH inhibitors was investigated in both estrogen receptor (ER)+ and ER‑ breast cancer cell lines and in normal breast epithelial cells.
[Molecular Medicine Reports] |
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The authors found that, in addition to its cytotoxic effects, bruceine A significantly inhibited the invasion and migration capabilities of two types of breast cancer cell lines while concurrently promoting apoptosis in these cells.
[Chemical Biology & Drug Design] |
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| Scientists describe the roles of extracellular vesicles in tumor immune microenvironment, metabolic microenvironment, and vascular remodeling.
[Molecular Therapy Oncology] |
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| The Research Institute of the McGill University Health Centre will host a new Phase III randomized clinical trial called TROPION-Breast04, as announced by the McPeak-Sirois Group, a provincial consortium of cancer centres across Quebec focused on breast cancer research.
[McGill University Health Centre] |
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| January 22 – 25, 2024
Santa Fe, New Mexico, United States |
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| | Zhejiang Chinese Medical University – Hangzhou, China |
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| | BC Cancer – Vancouver, British Columbia, Canada |
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| | Swammerdam Institute for Life Sciences – Amsterdam, Netherlands |
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| | NIH National Cancer Institute – Bethesda, Maryland, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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