 | | Vol. 16.01 – 11 January, 2024 |
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| NCK promoted apoptosis and G0/G1 cell cycle arrest of TNBC cell lines in vitro, concordant with gene expression analyses, and reduced in vivo xenograft growth and metastatic burden, demonstrating efficacy as a single agent.
[NPJ Precision Oncology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators showed that Divalent Metal Transporter 1 (DMT1) sustained mitochondrial iron translocation via early endosome-mitochondria interactions in triple-negative MDA-MB-231, but not in luminal A T47D breast cancer cells.
[Oncogene] |
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| Investigators reported a strong downregulation of epithelial Wnt/β-catenin activity as the mammary bud progresses to branching. They showed that forced activation of epithelial β-catenin severely compromised embryonic mammary gland branching.
[Journal Of Investigative Dermatology] |
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| Scientists identified zonula occludens-1 (ZO-1) as a specific intrinsic molecule that played a vital role in mediating the collective migration of mesenchymal stem cells towards breast tumor cells and transforming growth factor beta, which was a crucial factor secreted by breast tumor cells.
[Cell Death Discovery] |
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| Researchers reported that the endocannabinoid-degrading enzyme fatty acid amide hydrolase played a pivotal role in adult mammary gland development.
[Cell Death Discovery] |
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| Investigators evaluated the role of the indoleamine-2,3-dioxygenase (IDO) and aryl hydrocarbon receptor (AHR) blockers on cell migration, clonogenic, and IDO expression of murine breast cancer cells. The cell migration and clonogenic abilities of breast cancer cells were evaluated.
[Immunologic Research] |
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| Salicylic acid was dopped into poly(3-hydroxybutyrate) and prepared nanoparticles to increase encapsulation efficiency, anti-cancer activity of caffeic acid, and folic acid for breast cancer treatment.
[Journal Of Microencapsulation] |
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| Sanguinarine, HPMC-NPs, and doxorubicin were tested on Adriamycin-resistant MCF-7/ADR breast cancer cells, parent-sensitive MCF-7, and MCR-5 normal cells
[Drug Development And Industrial Pharmacy] |
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| Scientists investigated the effect of histone lysine demethylase 3 A (KDM3A) expression with TNBC invasion and metastasis. In our results, knockout of KDM3A in TNBC MDA-MB-231 cells promoted apoptosis and inhibited the proliferation, invasion, and metastasis of MDA-MB-231 cells.
[Journal Of Molecular Histology] |
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| Scientists described key steps in the development of the modern paradigm for the treatment of HER2-positive advanced-stage breast cancer, including selecting and sequencing new-generation HER2-targeted therapies, and summarize efficacy and safety outcomes from pivotal studies.
[Nature Reviews Clinical Oncology] |
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| The authors provide an in-depth review of the advancement of Lipocalin 2 (LCN2) in the context of breast cancer occurrence and development.
[Biomedicine & Pharmacotherapy] |
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| “From training Zambia’s first breast radiologists and testing AI-supported breast cancer diagnosis in Nigeria to implementing novel approaches for addressing cervical cancer in Cameroon and Mexico, the Prevent Cancer Foundation is proud to support the 2024 Global Innovation Grants,” said CEO Jody Hoyos.
[Prevent Cancer Foundation] |
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| February 22 – 24, 2024
Austin, Texas, United States |
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| | Princeton University – Princeton, New Jersey, United States |
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| | Human Technopole – Milan, Italy |
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| | University of Melbourne – Melbourne, Australia |
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| | Zhejiang Chinese Medical University – Hangzhou, China |
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| | BC Cancer – Vancouver, British Columbia, Canada |
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