 | | Vol. 16.05 – 8 February, 2024 |
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| Researchers utilized a combination of synthetic bone matrix models with controlled mineral content, nanoscale optical imaging, and flow cytometry to evaluate how collagen type I mineralization affected the biochemical and biophysical properties of the tumor cell glycocalyx.
[Advanced Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors employed an unbiased chromatin immunoprecipitation-based proteomic technique to identify endogenous androgen receptor (AR) interacting co-regulatory proteins in estrogen receptor positive and negative models of breast cancer to gain new insight into mechanisms of AR signaling in this disease.
[Genome Biology] |
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| Investigators reconstructed rhythms informatically, integrating locally collected, time-stamped biopsies with public datasets. For noncancerous breast tissue, inflammatory, epithelial–mesenchymal transition, and estrogen responsiveness pathways show circadian modulation.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Scientists defined the role of NF1 deficiency in estrogen receptor (ER)-positive breast cancer metabolic reprogramming and identified potential targeted pathway and metabolic inhibitor combination therapies for NF1-deficient ER + breast cancer.
[Molecular Metabolism] |
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| Researchers focused on breast cancer to examine the influence of alpha-1,3-mannosyltransferase (ALG3)-mediated signaling pathways and intercellular interactions in the advancement of tumors. The biological effects of ALG3 were verified by breast cancer cells.
[Aging] |
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| Investigatorss appraised the synergetic effect of doxorubicin and naringin and explored the underlying mechanism. The cytotoxicity of doxorubicin and naringin on MCF-7 was monitored.
[Scientific Reports] |
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| The authors elucidated the influence of the lncRNA small nucleolar RNA host gene 1 (SNHG1) on breast cancer progression and its underlying mechanism. The findings revealed a conspicuous up-regulation of SNHG1 in both breast cancer tissues and cells.
[Scientific Reports] |
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| Investigators used primary bovine mammary epithelial cell cultures extracted noninvasively from bovine milk samples to monitor the cellular responses to Escherichia coli challenge.
[Veterinary Research] |
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| Researchers utilized single-cell transcriptional profiling to delineate responses of murine and human normal breast organoid systems to female hormones across evolutionary distinct species.
[Journal Of Mammary Gland Biology And Neoplasia] |
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| As the cancer immunology field is moving toward the analysis of the TIME at the cellular and spatial levels, scientists highlight key studies that revealed previously unappreciated complexity in breast cancer using these technologies.
[Cold Spring Harbor Perspectives In Medicine] |
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| A group of researchers, led by Assoc Prof Ng Yin Kwee from NTU’s School of Mechanical and Aerospace Engineering, has developed a computer program to identify potential tumors in the human breast, making use of the observation that malignant breast tumors distribute heat differently to healthy breast tissue.
[Nanyang Technological University] |
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| University of Nottingham Malaysia associate professor Dr. Ho Weang Kee has been granted a Wellcome Trust Career Development Award amounting to RM11.3 million to be utilized to advance groundbreaking breast cancer risk stratification and communication techniques tailored for diverse Asian populations.
[The Sun] |
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| China and the United States will once again probably delay the renewal of a decades-old pact to cooperate on science and technology. The two nations have been negotiating for the past six months, but need more time to settle new terms and conditions requested by both sides, sources tell Nature.
[Nature News] |
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| March 24 – 29, 2024
Galveston, Texas, United States |
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| | Dana-Farber – Boston, Massachusetts, United States |
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| | National Cancer Institute – Bethesda, Maryland, United States |
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| | University of Nottingham – Nottingham, England, United Kingdom |
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| | Karolinska Institutet – Solna, Sweden |
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| | University of Birmingham – Birmingham, England, United Kingdom |
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