 | | Vol. 16.16 – 25 April, 2024 |
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| Scientists reported that procoagulant platelets beared large amounts of immune checkpoint molecules and that the presence of these cellular blood components in TNBC related to pro-tumorigenic immune cell activity and impaired survival.
[Blood] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators highlighted CXCL1EV-dead as a novel dying cell-released signal and provided TPCA-1 as a targeting candidate to improve TNBC prognosis.
[Journal Of Experimental & Clinical Cancer Research] |
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| The effect of tachyzoites of T. gondii on human breast cancer cells proliferation and migration was assessed using cell growth curve and wound healing assays.
[Cancer Cell International] |
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| To develop a novel PET imaging agent, we prepared gallium-68 (68Ga) labeled-DOTA-SD01 and evaluated its specificity and effectiveness through micro PET/CT imaging in a TNBC-bearing mouse model.
[Dalton Transactions] |
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| Researchers reported the synthesis and biological evaluation of fluorine-containing triazole derivatives as potent lysophosphatidic acid receptor 1 (LPA1) antagonists, offering potential as migrastatic drugs for triple negative breast cancer.
[ChemMedChem] |
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| Investigators determined whether these two proteins were present in intracellular complexes in breast carcinoma cells. Evaluation using molecular docking indicated that HIF-1α and RAB22A interact with each other.
[Molecular Biology Reports] |
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The authors describe the regulatory mechanism of the miRNA-192 family affecting the malignant behavior of breast cancer cells and evaluate the value of the miRNA-192 family as a diagnostic and prognostic biomarker for breast cancer.
[Biomedicine & Pharmacotherapy] |
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| Evexta Bio SA provided an update on the clinical development of its lead asset, rupitasertib, a selective oral inhibitor of S6K and AKT1/AKT3.
[Evexta Bio SA] |
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| May 29 – June 1, 2024
Vancouver, British Columbia, Canada |
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| | University of Miami – Miami, Florida, United States |
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| | University of Pittsburgh – Pittsburgh, Pennsylvania, United States |
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| | Indiana University School of Medicine – Indianapolis, Indiana, United States |
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| | Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| | Indiana University School of Medicine – Indianapolis, Indiana, United States |
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