Mammary Cell News Volume 17.11 | Jun 19 2025

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    Jamie Kang
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    2025-06-19 | MCN 17.11


    Mammary Cell News by STEMCELL Technologies
    Vol. 17.11 – 19 June, 2025
    TOP STORY

    CREPT Is Required for the Metastasis of Triple-Negative Breast Cancer through a Co-Operational-Chromatin Loop-Based Gene Regulation
    Researchers reported that CREPT/RPRD1B, which exhibits somatic gene copy-number amplifications and elevated expression, correlated with poor patient survival and drives TNBC metastasis.
    [Molecular cancer]
    Full ArticleGraphical Abstract
    Tips to prepare for your next conference or networking event
    PUBLICATIONSListed by the impact factor of the journal

    Multi-Omics Analyses of the Heterogenous Immune Microenvironment in Triple-Negative Breast Cancer Implicate UQCRFS1 Potentiates Tumor Progression
    Scientists offered perspectives on comprehending the heterogeneity within the tumor immune microenvironment of TNBC, thereby facilitating the elucidation of TNBC biology and providing clinical recommendations for TNBC patients’ prognosis.
    [Experimental Hematology & Oncology]
    Full Article

    Nanoscale Structural Dynamics of Cell Edges in Breast Tumor Cells Revealed by Scanning Ion Conductance Microscopy
    Researchers utilized time-lapse scanning ion conductance microscopy to visualize subcellular nanoscale structural dynamics at the edges of breast cancer cells.
    [Nanoscale]
    AbstractGraphical Abstract

    An Antibody-Photosensitiser Bioconjugate Overcomes Trastuzumab Resistance in HER2-Positive Breast Cancer
    Investigators explored the use of photodynamic therapy with a trastuzumab-IRDye700DX photoimmunoconjugate as a strategy to overcome trastuzumab resistance.
    [European Journal of Medicinal Chemistry]
    AbstractGraphical Abstract

    Novel Chloropyridazine Sulfonamides As Aromatase Inhibitors and Apoptotic Inducers in Breast Cancer
    Scientists combined sulfonamide, chloropyridazine, and pyrrole in a single design as potential aromatase inhibitors for breast cancer.
    [Bioorganic Chemistry]
    AbstractGraphical Abstract
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    REVIEWS

    Integrating PET/CT into Breast Cancer Care: A Review of Recent Developments
    The authors explore the role of PET/CT in breast cancer (BC) management and emerging radiotracers for enhanced diagnosis. They examine how 1 8 F-FDG-PET/CT findings are influenced by BC classifications such as histopathological type, grade, receptor status, and stage.
    [Expert Review of Anticancer Therapy]
    Abstract
    INDUSTRY AND POLICY NEWS

    Arvinas Announces Submission of New Drug Application to US FDA for Vepdegestrant for Patients with ESR1-Mutated ER+/HER2- Advanced or Metastatic Breast Cancer
    Arvinas, Inc. announced the submission of a New Drug Application to the US FDA with its partner Pfizer Inc., for vepdegestrant for the treatment of patients with ER+/HER2- ESR1-mutated advanced or metastatic breast cancer previously treated with endocrine-based therapy.
    [Arvinas, Inc.]
    Press Release
    FEATURED EVENT

    5th Next Generation Gene Therapy Vectors Summit
    July 29-31, 2025
    Boston, Massachusetts, United States

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    JOB OPPORTUNITIES

    Postdoctoral Research Associate – Lung and Mammary Gland
    Princeton University – Princeton, New Jersey, United States

    Professor – Cancer Cell Biology
    University of Southampton – Southampton, England, United Kingdom

    Research Associate – Bioinformatics
    University of Cambridge – Cambridge, England, United Kingdom

    Senior Research Associate – Multimodal Machine Learning for Breast Cancer Research
    University of Cambridge – Cambridge, England, United Kingdom

    Assistant/Associate/Full Professor – Cancer Biology
    Indiana University – Bloomington, Indiana, United States

    > See All Jobs

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