 | | Vol. 12.28 – 21 July, 2020 |
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| Neuregulin 1 robustly stimulated proliferation in crypts and induced budding in organoids, in part through elevated and sustained activation of mitogen-activated protein kinase and AKT.
[Cell Stem Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated whether the therapeutic potential of an acellular porous scaffold made of type I collagen could be improved by the addition of a powerful trophic agent in the form of mesenchymal stromal cells conditioned medium in order to be used as an acellular scaffold for skin wound healing treatment.
[Journal of Cellular and Molecular Medicine] |
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| The authors demonstrated the potency of the mechanically stimulated osteocyte secretome in driving human bone marrow stem/stromal cell recruitment and differentiation.
[Stem Cells Translational Medicine] |
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| Scientists designed multifunctional cell therapy microcarriers with the capability of sequential delivery of essential growth factors, bone morphogenetic protein 2 and vascular endothelial growth factor.
[Scientific Reports] |
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| The authors characterized the hematopoietic supporting activity of mesenchymal stromal cells‐derived osteoblast (M‐OST) conditioned media by comparing the secretome of M‐OST to that of their precursor.
[Proteomics] |
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| Investigators describe a new histological method based on iron hematoxylin combined with Oil red O staining, for the determination of the adipogenic differentiation of adipose-derived mesenchymal stem/stromal cells cultivated on a collagen-based 2D scaffold.
[Histochemistry and Cell Biology] |
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| Using genetically modified mouse models, scientists demonstrated that Wnt signaling promoted c-Fos-induced osteosarcoma formation via the actions of the collagen-modifying enzyme Loxl2.
[Cell Research] |
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| Scientists report eight mesenchymal tumors involving the gastrointestinal tract with NTRK1 or NTRK3 rearrangements.
[Modern Pathology] |
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| Chitosan scaffolds were implanted at the fracture site in a mouse model of intramedullary rod-fixed tibial fracture.
[Scientific Reports] |
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| The authors briefly summarize the development of MSCs as a treatment for human diseases as well as describe the present understanding of exosomes, how they exert their effects on target cells, and how they are differentiated from other extracellular vesicles.
[Frontiers in Cell and Developmental Biology] |
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| Following a marathon EU summit in Brussels, national leaders agreed to a €1.8 trillion, seven-year budget and pandemic recovery fund that will spend €81 billion on Horizon Europe, the main EU research program.
[Science Insider] |
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| Early data on the effects of the coronavirus pandemic on scientific-publishing output suggest that female researchers, particularly those at early-career stages, are the hardest hit. Submissions to preprint servers, such as arXiv, rose more quickly for male authors than for female authors as nations adopted social-isolation measures.
[Nature News] |
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| Come August, hundreds of universities across the United States are poised to reopen their campuses with a mix of online and in-person courses. Only a handful are aiming for an entirely online semester. But as the machinery of higher education cranks back into action, faculty, staff, and students are voicing concerns that, with COVID-19 cases surging in many parts of the country, employees are being forced to put their health-and the health of others-at unnecessary risk.
[Science Insider] |
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| September 8 – September 11
Virtual |
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| | KU Leuven – Leuven, Belgium |
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| | University of Connecticut Health – Farmington, Connecticut, United States |
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| | Helmholtz Zentrum München – Neuherberg, Germany |
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| | Memorial Sloan Kettering Cancer Center – New York, New York, United States |
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| | Genezen Laboratories – Indianapolis, Indiana, United States |
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