 | | Vol. 12.32 – 18 August, 2020 |
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| Investigators demonstrated that aging was associated with progressive loss of skeletal stem-cells and diminished chondrogenesis in the joints of both mice and humans.
[Nature Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated the effect of low-intensity pulsed ultrasound on the proliferation of human adipose-derived mesenchymal stromal cells and uncovered its stimulation mechanism.
[Scientific Reports] |
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| Exosomes isolated form adipose tissue derived mesenchymal stem cells were transfected with miR-10a and added to naïve T cells purified from mouse spleen.
[Life Sciences] |
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| Researchers tested the ability of adeno-associated viral (AAV) vectors carrying the cDNA for BMP-2 to transduce human mesenchymal stem cells, produce BMP-2, and induce osteogenesis in vitro as compared with lentiviral gene therapy with a two-step transcriptional amplification system lentiviral vector.
[Gene Therapy] |
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| Scientists examined the impact of heparin and collagen I multilayers on the growth, morphology and secretome of bone marrow and adipose-derived human mesenchymal stromal cells.
[Journal of Biomedical Materials Research Part A] |
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| Researchers showed that upon subcutaneous transplantation in mice, MSC formed multicellular aggregates and did not migrate significantly from the site of injection.
[Journal of Cellular and Molecular Medicine] |
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| Investigators prove that the in vivo activity of the whole secretome formulated in a sponge-like alginate wound dressing to obtain the controlled release of bioactive substances.
[European Journal of Pharmaceutics and Biopharmaceutics] |
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| The authors cover the latest advances in the understanding of the molecular mechanisms that regulate fibroblast growth factor signaling during normal joint development and in the pathogenesis of osteoarthritis.
[Nature Reviews Rheumatology] |
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| Scientists discuss the potential of therapeutic strategies targeting the biological functions of selenium and selenoproteins for osteoarthritis treatment.
[Experimental and Molecular Medicine] |
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| TRACON Pharmaceuticals, Inc. announced the clearance of the pivotal ENVASARC protocol after filing the protocol with the FDA as part of an Investigational New Drug application.
[TRACON Pharmaceuticals, Inc.] |
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| October 20 – October 21
Virtual |
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| | University of Copenhagen – Copenhagen, Denmark |
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| | Pennsylvania State University – Philadelphia, Pennsylvania, United States |
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| | University of Connecticut Health – Farmington, Connecticut, United States |
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| | Heidelberg Institute for Stem Cell Technologies and Experimental Medicine – Heidelberg, Baden-Württemberg, Germany |
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| | University of North Carolina at Chapel Hill – Chapel Hill, North Carolina, United States |
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