 | | Vol. 13.09 – 9 March, 2021 |
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| In rodent models of myocardial infarction, scientists demonstrated that intrapericardial injection was an effective and safe method to deliver hydrogels containing induced pluripotent stem cells-derived cardiac progenitor cells or MSC-derived exosomes.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors designed a substrate with a dual anisotropic structure fabricated via a combination of 3D printing and magnetic field-induced magnetic nanoparticle assembly techniques. These dual anisotropic structures had a scale hierarchy, and the scale of the magnetic nanoparticle assemblies matched that of a single adipose tissue-derived stem cells.
[NPG Asia Materials] |
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| Researchers investigated the role of ubiquitin-specific protease 53 in the osteogenic differentiation of human bone marrow-derived MSCs.
[Cell Death & Disease] |
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| The authors investigated the potential immunomodulatory effects of MSCs on group 2 innate lymphoid cells in peripheral blood mononuclear cells from allergic rhinitis patients and healthy subjects.
[Stem Cells] |
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| Investigators examined the influence of vitamin D3 (VitD3) on the angiogenic potential of MSCs. VitD3 treatment increased the expression of proangiogenic molecules in MSCs, which exhibited an endothelial cell-like phenotype and promoted vascularization in vitro and in vivo.
[iscience] |
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| Researchers used stringent case and control selection criteria and collected menstrual blood from women with a laparoscopic diagnosis of advanced endometriosis and from fertile women without endometriosis.
[Scientific Reports] |
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| Investigators examined the kinetics of intravascularly administered mesenchymal stem/stromal cells in the pulmonary vasculature using a microfluidic system in vitro and intra-vital microscopy of intact mouse lung.
[Scientific Reports] |
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| The authors showed that ubiquitin-specific protease 34 (USP34) plays a pivotal role in root formation. Deletion of Usp34 in dental mesenchymal cells led to short root anomaly, characterized by truncated roots and thin root dentin.
[International Journal of Oral Science] |
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| Downregulating chitinase-3-like protein 1 mitigated the ability of human umbilical cord-MSCs to inhibit T cell activation, proliferation and inflammatory cytokine secretion in vitro.
[Cell Death & Disease] |
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| Scientists genetically edited MSCs to overexpress bone morphogenetic protein 9 (BMP-9) using CRISPR-Cas9 to generate iMSCs-VPRBMP-9+, followed by in vitro evaluation of osteogenic potential and in vivo enhancement of bone formation in rat calvaria defects.
[Gene Therapy] |
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| Researchers discuss the characteristics and benefits of MSC therapy as well as MSC-secreted exosome therapy in treatment of COVID-19 patients.
[Clinical Immunology] |
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| Novadip Biosciences announced that the FDA has approved the company’s Investigational New Drug (IND) application for its autologous cell therapy product NVD‑003 for the treatment of Congenital Pseudarthrosis of the Tibia.
[Novadip Biosciences (GlobeNewswire, Inc.)] |
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| June 14 – 18, 2021
Virtual |
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| | National University of Ireland Galway – Galway, Ireland |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | University of Southern Denmark – Odense M, Denmark |
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| | Karolinska Institutet – Flemingsberg, Sweden |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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