 | | Vol. 14.24 – 21 June, 2022 |
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| Scientists reported a comparative genetic analysis of 2,138 sarcomas representing 45 pathological entities. This cohort was prospectively analyzed using targeted sequencing to characterize subtype-specific somatic alterations.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that a scaffold of nanowires, which were remotely actuated by a magnetic field, mechanically stimulated MSCs.
[Journal of Nanobiotechnology] |
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| Investigators confirmed that the expression level of lncRNA RAD51-AS1 in bone marrow MSCs from patients with osteoporosis was significantly lower than those from healthy donors.
[Stem Cell Reviews and Reports] |
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| Scientists established a double-stranded locked nucleic acid/DNA nanobiosensor for gene expression analysis in single human MSCs in both 2D and 3D microenvironments.
[Scientific Reports] |
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| The authors developed biocompatible alginate- and silk-based bioinks to print self-standing structures with the ability of spatially controlled differentiation of the encapsulated human MSCs.
[ACS Applied Bio Materials] |
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| Investigators found that circ_0003204 was significantly downregulated during osteogenic differentiation of human adipose-derived stem cells.
[International Journal of Oral Science] |
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| Researchers differentiated induced pluripotent stem cells (iPSCs) into MSC-like cells as a potential substitute for adult MSCs and evaluated its effect on non-small cell lung cancer.
[Journal of the Chinese Medical Association] |
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| Scientists employed single-cell RNA sequencing to characterize the immune composition of an undifferentiated pleiomorphic sarcoma mouse model, showing that macrophages in the sarcoma mass exhibited distinct activation states.
[Cell Reports] |
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| Researchers explored the effects of secretome or conditioned medium derived from human embryonic stem cell-derived MSCs on hippocampal neurogenesis, inflammation, and apoptosis in experimental stroke.
[CNS Neuroscience & Therapeutics] |
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| The authors reported that the matrix metalloproteinase 13 (MMP13) was the highest up-regulated gene in mesenchymal cells from mice lacking the estrogen receptor alpha.
[Scientific Reports] |
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| Investigators discuss the role and therapeutic potential of MSCs and the challenges ahead in using them to treat viral infections, highlighting the COVID-19 infection.
[Stem Cell Research & Therapy] |
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| Scientists describe the role of MSCs and underlying mechanisms in regulating astrocytes-related amyloid-β metabolism, neuroinflammation, and synapse dysfunction in early Alzheimer’s disease, exploring the open questions in this field.
[Frontiers in Neuroscience] |
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| UC Davis innovators in stem cells, methane reduction, and education access were honored with Chancellor’s Innovation Awards.
[The University of California, Davis] |
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| December 8 – 10, 2022
Los Angeles, California, United States |
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| | National University of Ireland Galway – Galway, Ireland |
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| | The Ohio State University Comprehensive Cancer Center – Columbus, Ohio, United States |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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| | Stem Cell Network – Ottawa, Ontario, Canada |
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| | China Medical University – Shenyang, China |
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