 | | Vol. 14.32 – 16 August, 2022 |
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| The authors isolated c-kit+VEGFR-2+ cells from rat bone marrow-derived MSCs, and assessed potential of c-kit+VEGFR-2+ MSCs to differentiate towards cardiovascular cells and their efficiency of repairing the infarcted myocardium after transplantation.
[Stem Cell Reviews and Reports] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists designed a study to detect mitochondrial and lysosomal activity, morphological, and functional changes in human umbilical cord MSCs after long-time culture.
[Stem Cell Research & Therapy] |
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| Mechanistic studies demonstrated that serum angiopoietin-like protein 8 (ANGPTL8) could promote the differentiation of MSCs into adipocytes by inhibiting the Wnt/β-Catenin pathway and upregulating PPARγ and c/EBPα mRNA expression.
[Frontiers in Endocrinology] |
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| Researchers reported that Pluronic F-127/human adipose-derived MSCs-exosome complexes enhanced skin wound healing, promoted re-epithelialization, up-regulated expression of skin barrier proteins, and reduced inflammation.
[Stem Cell Research & Therapy] |
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| Scientists investigated the synergistic effect of bone marrow MSCs and estrogen on improving the endometrial regeneration and restoring the endometrium morphology and its underlying molecular mechanisms.
[Reproductive Biology and Endocrinology] |
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| The authors measured 3D encapsulated human MSC migration and remodeling in a well-characterized hydrogel with a step-change in stiffness.
[Soft Matter] |
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| Interaction of MSCs with platelets in cell-to-cell contact dependent manner was essential for their migration, thereby, vascular-mimicry.
[Cytokine] |
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| To develop reliable scaffold-free periodontal tissue regenerative cell therapy by MSCs/extracellular matrix complexes (C-MSCs), scientists investigated the periodontal tissue regenerative capacity of C-MSCs and the behavior of the transplanted cells.
[Journal of Tissue Engineering and Regenerative Medicine] |
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| Researchers evaluated and compared the healing potential of MSCs derived from two common sources, iliac crest derived bone marrow and omental fat, in a full thickness skin wound model.
[Current Research in Translational Medicine] |
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| Investigators summarize the significant advances into the upstream processing, mainly the dynamic generation and cultivation of MSC aggregates, for the conditioned medium manufacture and focus on the standardization of the soluble factor production.
[Frontiers in Bioengineering and Biotechnology] |
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| Ipsen announced the closing of the definitive merger agreement under which Ipsen has acquired Epizyme, Inc.
[Ipsen] |
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| Research to help improve memory in children with intellectual disabilities is one of several Western research projects receiving more than $7.6 million in funding from the Canadian Institutes of Health Research.
[Western University] |
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| | University of Turin – Torino, Italy |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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| | Shenzhen Institute of Advanced Technology – Shenzhen, China |
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| | National University of Ireland Galway – Galway, Ireland |
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| | Cedars-Sinai – Los Angeles, California, United States |
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