 | | Vol. 14.38 – 27 September, 2022 |
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| In colony forming assays, the Tbx1neo2/neo2-derived mesenchymal cells had reduced expansion potential, contrasting the normal growth of thymus epithelial cells.
[Journal of Clinical Investigation] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists identified an SFRP4+ stromal cell subpopulation that was highly enriched in the regenerative stage of the human endometria during the menstrual cycle.
[Cell Discovery] |
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| Knockdown of AF4/FMR2 family member 4 (AFF4) in human MSCs and mouse 3T3-L1 preadipocytes inhibited cellular adipogenic differentiation.
[PLoS Genetics] |
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| Scientists demonstrated that human fetal membrane-MSCs could give rise to spinal motor neurons, by the sequential exposure to specific factors that induced a neuralization, caudalization, and ventralization of undifferentiated cells.
[iScience] |
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| Investigators describe a facile method to fabricate vascularized constructs using chitosan and gelatin-based microgels that promote osteogenesis of human MSCs while supporting endothelial sprouting and network formation.
[Scientific Reports] |
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| Chondrogenic potentials of 3D high-density cultures of bone marrow and Wharton’s jelly-derived MSCs was investigated by chondrogenesis- and cytokine-related gene expression over a 16-day culture period supplemented with human transforming growth factor.
[Frontiers in Bioengineering and Biotechnology] |
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| The authors evaluated how glucose and fructose affected the adipose differentiation of pig newborn MSCs. MSCs displayed adipose morphology after 70 days of differentiation.
[Journal of Food Biochemistry] |
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| Mice were injected intravenously with superparamagnetic iron oxide-labeled MSCs at two hours after Escherichia coli infection and sacrificed at different times to investigate their distribution and therapeutic effect.
[Cell Death & Disease] |
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| The authors developed a single-cell 3D spatial correlation method to track transplanted MSCs based on deep tissue microscopy of fluorescent nanoparticles and immunofluorescence of key proteins.
[Stem Cell Reports] |
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| Researchers investigated the impact of LPS pretreated human adipose-derived MSCs on skin wound healing in diabetic rats.
[injury-International Journal of the Care of the injured] |
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| Investigators provide an overview of the characteristics and potentials of MSC as well as the use of MSC-derived exosomes in cancer therapy.
[Frontiers in Bioengineering and Biotechnology] |
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| Cynata Therapeutics Limited announced that the Australian Government National Health and Medical Research Council has awarded a grant of approximately $1 million to fund a major preclinical research project to investigate Cynata’s Cymerus™ MSCs as a treatment for ischaemic heart disease.
[Cynata Therapeutics Limited (BioSpace)] |
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| November 2 – 4, 2022
Lyon, France |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | UC San Francisco – San Francisco, California, United States |
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| | Karolinska Institutet – Flemingsberg, Sweden |
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