 | | Vol. 14.42 – 25 October, 2022 |
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| Investigators described an advanced magnetothermal approach to label MSCs efficiently by local induction of heat-enhanced membrane permeability for magnetic resonance imaging tracking and targeted therapy of stroke.
[ACS Nano] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers characterized the secreted proteins of muscle-derived MSCs (mdMSCs) in an in vitro model of osteoarthritis to evaluate the putative clinical interest of mdMSCs as cell therapy for joint diseases like osteoarthritis.
[Stem Cell Reviews and Reports] |
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| The authors investigated the role of heparan sulfate in endothelial differentiation and vasculogenesis of dental pulp stem cell.
[Journal of Dental Research] |
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| Scientists focused on the mechanisms of cell migration during mesenchymal cell condensation and the effects of matrix adherence.
[Journal of Cell Science] |
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| Human bone marrow-MSCs were separated into pluripotent-like SSEA-3(+) Muse cells and multipotent SSEA-3(-) MSCs and were subjected to single-cell RNA sequencing analysis.
[iScience] |
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| Investigators proposed an end-to-end deep learning framework for functional screening of MSC lines using live-cell microscopic images of MSC populations.
[Scientific Reports] |
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| Acute graft-versus-host disease induced the expression of E-selectin within lesional endothelial beds, and tissue-specific recruitment of systemically administered host-derived MSCs was achieved by enforced expression of HCELL, a CD44 glycoform that is a potent E-selectin ligand.
[npj Regenerative Medicine] |
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| Scientists compared the efficacy of two treatments, MSC with their miR-21 inhibited through lentiviral transfection and their extracellular vesicles, against inflammation in a new osteoarthritis (OA) animal model.
[Cellular and Molecular Life Sciences] |
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| Investigators examined the combination therapy of human mesenchymal stromal cells (MSCs) and endothelial colony-forming cells (ECFCs) to reduce the early ischemic damage and enhance angiogenesis in a pre-clinical model of acute myocardial infarction.
[Stem Cell Reviews and Reports] |
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| Rats with or without middle cerebral artery occlusion (MCAO) received intrathecal injections of 2D cultured MSCs, 3D cultured MSCs, or an equal volume of artificial cerebrospinal fluid.
[Stem Cell Research & Therapy] |
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| The authors focus on the main resources of MSCs, underlying therapeutic mechanisms, clinical applications, and efforts made to improve MSC-based cell therapy efficiency.
[Stem Cells International] |
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Pulthera, LLC has received notice from the US FDA Investigational New Drug that it can proceed with “A Phase IIb, Study to Assess the Efficacy, Safety, and Tolerability of Intravenous Allogenic Bone Marrow-derived MSCs in Subjects with Dyspnea Associated with Post-acute Sequelae of SARS-CoV-2 Infection.”
[Pulthera, LLC] |
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| February 9 – 12, 2023
Cancun, Mexico |
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| | Ume̴, Sweden РUme̴ University |
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| | Karolinska Institutet – Solna, Sweden |
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| | Eindhoven University of Technology – Eindhoven, Netherlands |
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| | Institute of Tissue Regeneration Engineering – Cheonan, South Korea |
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| | University of Colorado Denver – Aurora, Colorado, United States |
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