 | | Vol. 14.45 – 15 November, 2022 |
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| Investigators uncovered a nestin-negative mesenchymal neural crest-like subpopulation as a previously unknown malignant stem-like state common to murine and human malignant peripheral nerve sheath tumor (MPNST), which correlated with clinical severity.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists established a DNA-driven cell culture platform that could be programmed to present the RGD peptide from fibronectin, mimicking cell-extracellular matrix interactions, and the HAVDI peptide from N-cadherin, mimicking cell-cell interactions.
[Nature Communications] |
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| The authors showed that tumor necrosis factor alpha (TNF-α) promoted the endothelial differentiation of MSCs by inducing vascular endothelial growth factor receptor 2 (VEGFR2) gene expression.
[Cell Death & Differentiation] |
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| The functionalization of the multilayer with lipoplexes encapsulating DNA encoding for transient expression of bone morphogenetic protein 2 induced osteogenic differentiation of MSCs.
[Advanced Healthcare Materials] |
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| Researchers confirmed that the expression of ganglioside GD1a was significantly reduced in MSCs derived from LmnaDhe/+ mice and in MSCs subjected to Lamin A/C knockdown using small interfering RNA.
[Aging-Us] |
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| Long non-coding RNA (lncRNA) and mRNA microarrays were performed to study the change of gene expression during osteogenic differentiation of bone marrow-derived MSCs.
[Aging-Us] |
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| Investigators evaluated the proliferation and osteogenic differentiation potentials of MSCs cultured on two types of 3D-printed hydroxyapatite (HA), including a 3D-printed HA and biomimetic calcium phosphate-coated 3D-printed HA.
[Scientific Reports] |
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| Scientists found that co-administration of immunoproteasome-reprogrammed MSCs (IRMs) and interleukin-12 accentuated the anti-tumoral response, whereas the cross-presentation potency of IRMs was enhanced, delayed endosomal maturation, and increased endosome-to-cytosol plasticity.
[iScience] |
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| N6-methyladenosinemethylation in undifferentiated bone marrow MSCs was low and MIR99AHG overexpression abolished the effects of overexpressed METTL3 on promoting osteogenic differentiation.
[Cell Cycle] |
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| Olfactory mucosa-derived MSCs (OM-MSCs) were extracted and identified. The collected OM-MSCs were prepared after repeated freeze–thaw in phosphate buffer solution.
[BMC Pulmonary Medicine] |
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| Scientists review the homing effect of stem cells in joints and highlight progress toward the targeted modification of MSCs.
[Journal of Translational Medicine] |
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| Investigators provide an overview on the current understanding of the mechanisms on MSCs and their secretome regulating inflammation and immune cells after myocardial infarction and shed light on the applications of MSCs in the treatment of cardiac infarction.
[Cell Death Discovery] |
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| The authors highlight MSCs in cardiovascular mechanotransduction, differentiation of cardiomyocytes, and the use of MSCs in cardiovascular disease and tissue engineering.
[Heliyon] |
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| Amniotics AB announced it has been invited to finalize a grant agreement with the European Innovation Council (EIC) as part of a consortium set to receive a grant of €3,8 Million from the EIC Pathfinder program.
[Amniotics AB] |
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| February 5 – 8, 2023
Keystone, Colorado, United States |
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| | Institut Curie – Paris, France |
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| | Cancer Research UK Manchester Institute – Manchester, England, United Kingdom |
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| | Institute for Tumor Biology and Experimental Therapy – Frankfurt, Germany |
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| | NUI Galway – Galway, Ireland |
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| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
Prostate Cell News
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