 | | Vol. 14.47 – 30 November, 2022 |
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| Scientists identified the circular RNAs (circRNAs) expressed in soft tissue sarcoma cells and explored how the circRNAs regulated sarcoma growth in vivo.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators evaluated the impact of fibrin glue addition to biologic membranes loaded with bone marrow-derived MSCs (B-MSCs). B-MSCs were harvested from three different unrelated donors.
[Scientific Reports] |
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| Researchers demostrated that human bone marrow-derived cells (BMDCs) could rapidly adopt a neural-like morphology through active neurite extension, and binucleated human BMDCs could form with independence of any cell fusion events.
[Scientific Reports] |
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| The authors investigated the effects of BTB and CNC homology 1 (BACH1) on the proliferation and odontoblastic differentiation of human dental pulp stem cells in vitro.
[BMC Oral Health] |
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| Investigators explored the specific mechanism of miR-145 involved in steroid-induced osteonecrosis of femoral head. Dexamethasone, a typical glucocorticoid, was used to induce osteogenic differentiation of bone marrow MSCs.
[BMC Musculoskeletal Disorders] |
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| Researchers found that subcutaneous application of umbilical cord-derived MSCs primed by interferon-γ and tumor necrosis factor-α exhibited remarkable therapeutic efficacy on imiquimod-induced psoriasis-like inflammation in mice.
[Cell Death & Disease] |
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| Investigators loaded mouse bone marrow-derived MSCs with adenovirus (Ad)5-Ki67/IL-15 and observed the transduction, replication, and release of Ad5-Ki67/IL-15 in MSCs.
[Biomedicine & Pharmacotherapy] |
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| Scientists found that interferon-γ – and tumor necrosis factor-α-pretreated MSCs significantly alleviated skin fibrosis in a bleomycin-induced systemic sclerosis model.
[Cell Death Discovery] |
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| Researchers investigated the therapeutic effects and mechanisms of treatment of bone marrow-MSC derived from C57BL/6 on the topoisomerase I induced systemic sclerosis associated with lung interstitial lung disease like mice model.
[Cell and Tissue Research] |
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| The authors discuss nine essential transcription factors involved in osteoblast differentiation, including Runx2, Osx, Dlx5, β-catenin, ATF4, Ihh, Satb2, and Shn3.
[Journal of Biomolecular Structure and Dynamics] |
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| Kala Pharmaceuticals, Inc. announced the submission of an investigational new drug application to the US FDA for KPI-012, a human MSC secretome, for the treatment of persistent corneal epithelial defect.
[Kala Pharmaceuticals, Inc.] |
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| January 23 – 25, 2023
Breckenridge, Colorado, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | City of Hope – Los Angeles, California, United States |
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| | Takeda – Boston, Massachusetts, United States |
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| | Institut Curie – Paris, France |
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| | Uppsala University – Uppsala, Sweden |
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