 | | Vol. 15.00 – 3 January, 2023 |
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| The authors investigated the effect of viscoelasticity on the migration and fusion behavior of MSC spheroids using hydrogels with similar elasticity but different stress relaxation profiles.
[Bioengineering & Translational Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the effects of pharmaceutical activation of AMPK, an essential regulator of energy metabolism, on mitochondrial programming of Wharton’s Jelly MSCs from women with diabetes during pregnancy.
[Stem Cells and Development] |
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| The authors investigated the effects of TAZ in BMP9-induced osteogenic differentiation of MSCs and murine multi-lineage cell lines C2C12 and MEFs and explored its possible mechanisms.
[Cell Death Discovery] |
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| Overexpression of MEG3 and TNFAIP3 or inhibition of miR-125a-5p was found to inactivate the Wnt/β-catenin pathway, thus suppressing osteogenic differentiation of MSCs.
[Apoptosis] |
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| Scientists investigated the expression pattern of Mage-D1 in rat dental germ development and its differential mineralization ability to ectomesenchymal stem cells.
[Scientific Reports] |
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| Investigators demonstrated that C5L2 modulated brain-derived neurotrophic factor secretion in human dental pulp stem cells.
[Scientific Reports] |
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| Researchers revealed that palmitic acid inhibited Runx2 mRNA expression in human bone marrow MSCs and identified ZDHHC16 as a potential target palmitoyl acyltransferase.
[Heliyon] |
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| The application of human dental pulp stem cells in 2D and 3D was performed by microsurgery, with subsequent functional assessment on rat models with spinal motor root avulsion.
[Brain Research] |
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| Researchers evaluated the effect of dentin matrix alone or combined with MSCs on postextraction alveolar bone regeneration.
[Clinical Oral Investigations] |
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| Scientists assessed whether the treatment of hyperammonemic rats with extracellular vesicles from MSCs restores cognitive function and analyzed the underlying mechanisms.
[Journal of Neuroinflammation] |
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| Investigators explore the potential of MSCs to aid in the recovery of patients with systemic inflammatory response syndrome and the pre-clinical and early clinical evidence generated to date.
[Clinical And Translational Medicine] |
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| Scientists review the recent understanding of atopic dermatitis (AD) pathology and advances in preclinical and clinical studies of MSCs, MSCs-derived conditional media, and exosomes as therapeutic tools to treat AD.
[Journal Of Cellular Biochemistry] |
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| Kala Pharmaceuticals, Inc. announced that the US FDA has accepted an investigational new drug (IND) application for KPI-012, a human MSC secretome, initially in development for the treatment of persistent corneal epithelial defect (PCED).
[Kala Pharmaceuticals, Inc.] |
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| January 29 – February 2, 2023
Banff, Alberta, Canada |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | Dankook University – Seoul, South Korea |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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| | UTHSC-Houston – Houston, Texas, United States |
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