 | | Vol. 15.02 – 18 January, 2023 |
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| With a 3D dynamic hydrogel using magneto-stimulation technology, scientists found that dynamic mechanical stimulation enhanced matrix-integrin β1 interactions which induced MSCs spreading and proliferation.
[Bioactive Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated how human bone-marrow-derived MSCs differentiated into early osteoblasts on a soft three-dimensional hydrogel.
[Advanced Healthcare Materials] |
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| Utilizing patient-derived and mouse model-derived samples, scientists determined the changes in mRNA and protein levels of genes and proteins associated with bone-marrow MSCs differentiation.
[Cell Death & Disease] |
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| Injectable Aldehyde-cellulose nanocrystalline/silk fibroin hydrogels containing polyetheretherketone were synthesized, and their bone regeneration capacity was evaluated.
[Scientific Reports] |
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| The authors analyzed the effect of a bioactive compound, alpha terpineol, on the differentiation of rat bone marrow derived MSCs toward neuronal lineage, and explored the regulation of its differentiation process through the study of Wnt pathway mediators.
[Cell Biochemistry And Function] |
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| Based on the “m6A site methylation stoichiometry” of m6A single nucleotide arrays, researchers identified 834 differential m6A-methylated genes in type 2 diabetes mellitus-bone marrow MSCs (BMSCs) compared with normal-BMSCs.
[International Journal of Oral Science] |
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| Investigators showed that Andrographolide-treated bone marrow MSCs (BMSCs)-conditioned medium (CM) could be more advantageous for cardiomyocyte injury repair than BMSCs-CM.
[Molecular Biology Reports] |
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| Scientists set up a rat model of chronic radiation cystitis and evaluated the efficacy of MSCs and their mode of action on chronic radiation cystitis.
[Stem Cell Research & Therapy] |
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| Investigators found that 200 mg/kg metformin increased bone marrow adipose tissue in mice tibia, and prompted osteogenic genes and lipogenic genes expression in murine bone marrow.
[Aging] |
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| Researchers extracted apoptotic extracellular vesicles derived from MSCs (MSCs-ApoEVs) to treat cardiotoxin-induced tibialis anterior injury and found that MSCs-ApoEVs promoted muscle regeneration and increased the proportion of multinucleated cells.
[International Journal Of Oral Science] |
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| Scientists elaborate on the studies pertaining to the application of MSCs in rheumatoid arthritis over the last two decades.
[Experimental Cell Research] |
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| New medicines need not be tested in animals to receive FDA approval, according to legislation signed by President Joe Biden in late December 2022.
[ScienceInsider] |
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| April 14 – 19, 2023
Orlando, Florida, United States |
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| | IRCCS Candiolo Cancer Institute – Turin, Italy |
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| | UCLA Jules Stein Eye Institute – Los Angeles, California, United States |
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| | Johns Hopkins University – Baltimore, Maryland, United States |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | Dankook University – Seoul, South Korea |
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