 | | Vol. 15.03 – 24 January, 2023 |
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| The authors found that lymphatic vessels in bone expanded during genotoxic stress. VEGF-C/VEGFR-3 signaling and genotoxic stress-induced IL6 drove lymphangiogenesis in bones.
[Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators showed that the sensory nerve was vital for mesenchymal tissue homeostasis and maintenance of MSCs in the continuously growing adult mouse incisor. Loss of sensory innervation led to mesenchymal disorder and a decrease in MSCs.
[Nature Communications] |
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| Blood vessel-derived extracellular matrix (VdECM) in hydrogel form was microscopically examined, tested for fibroblast proliferation, and examined for L/D staining. Cytokine array of various growth factors in adipocyte-derived mesenchymal stem cell media with VdECM was done.
[Tissue Engineering And Regenerative Medicine] |
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| The authors elucidated the role of apelin receptor signaling during mesoderm cell migration and differentiation from mouse embryonic stem cells.
[Human Cell] |
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| Scientists investigated the cellular and transcriptome profiles of MSCs isolated from the bone marrow microenvironment of an immunocompetent BCR-ABL1+ model of B cell acute lymphoblastic leukemia.
[Frontiers In Cell And Developmental Biology] |
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| Researchers found that the expression of miR-99b increased with increasing hydrogel stiffness and that miR-99b regulated the proliferation and differentiation of BMSCs seeded on the surface of substrates with different stiffnesses.
[APL Bioengineering] |
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| Scientists evaluated changes in microglia activation, neuron survival and proliferation of neural stem cells. Compared with the GFP group and the GFP-NT3 group, animals in the GFP-NT3P75 – 2 group exhibited better motor function improvements and milder neuroinflammation response.
[Neuroscience Letters] |
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| The authors evaluated the effects of β-catenin deletion in Axin2+ cells on cementogenesis. They generated triple transgenic mice to conditionally delete β-catenin in Axin2-lineage cells by crossing Axin2CreERT2/+; R26RtdTomato/+ mice with β-cateninflox/flox mice.
[Journal Of Periodontal Research] |
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| Investigators comprehensively review the deregulated miRNAs and impaired cellular functions in rheumatoid arthritis (RA) to shed light on several aspects of RA pathogenesis, with a focus on excessive inflammation, synovial hyperplasia and progressive joint damage.
[Bone Research] |
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| Stemedica Cell Technologies announced that it has initiated its Phase IIb/III, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of a single intravenous injection of allogeneic mesenchymal stem cells to subjects with ischemic stroke.
[Stemedica Cell Technologies] |
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| April 17 – 19, 2023
Freiburg im Breisgau, Germany |
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| | The Ottawa Hospital – Ottawa, Ontario, Canada |
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| | Dresden University of Technology – Dresden, Germany |
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| | IRCCS Candiolo Cancer Institute – Turin, Italy |
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| | UCLA Jules Stein Eye Institute – Los Angeles, California, United States |
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| | Johns Hopkins University – Baltimore, Maryland, United States |
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