 | | Vol. 15.06 – 14 February, 2023 |
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| The engineered exosomes modified for efficiently loading miR146a and attaching to silk fibroin patch were demonstrated to promote diabetic wound healing.
[Signal Transduction And Targeted Therapy] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| In vitro cytocompatibility of the composite was investigated using human adipose stem cells by MTT and lactate dehydrogenase assay, further assessed by SEM analysis and PKH26 staining.
[International Journal Of Biological Macromolecules] |
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| Scientists developed an image-based analytical tool using cell tracking, cytometric analyses, and gating with time-lapse microscopy to investigate the migratory behavior of human MSCs cultured on chitosan membranes.
[Biophysical Journal] |
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| Exosomes were isolated from overexpressed miR-146a/miR-155 MSCs . Splenocytes were isolated from collagen-induced arthritis and control mice.
[Biopreservation And Biobanking] |
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| Researchers investigated how viscoelasticity, a time-dependent mechanical property of collagen hydrogel, coordinated MSC cytoskeleton changes at different stages of chondrogenesis.
[Science Advances] |
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| Scientists constructed marrow adipogenic lineage precursors-deficient colony stimulating factor 1 (Csf1) CKO mice using AdipoqCre. These mice had increased femoral trabecular bone mass, but their cortical bone appeared normal.
[eLife] |
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| Investigators reported that CAR-T cell-mediated cytotoxicity was significantly inhibited in the presence of MSCs. MSCs caused an increase of CD4+ T cells and Treg cells but a decrease of CD8+ T cells.
[eLife] |
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| To establish a peri-implant fibrosis model, customized silicone implants were inserted into the dorsal site of C57BL/6 wild-type mice. Adipose-derived stem cells were harvested from the fat tissues of transgenic mice that expressed a green fluorescent protein and then injected into the peri-implant space of recipient mice.
[Stem Cell Research & Therapy] |
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| A novel therapeutic alternative involving amniotic MSC metabolite products has been developed using metabolites from stem cells which contain cytokines and growth factors.
[Journal Of Biological Engineering] |
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| Even though most studies use the International Society for Cell Therapy criteria, most publications in adult tissues don’t evaluate the characteristics that establish a stem cell, which will be necessary to distinguish between a stem cell and progenitor populations.
[Heliyon] |
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| MSCs are of particular interest because of their differentiation capacity, immunomodulatory effects, and their ability to migrate to sites of damage. MSCs can be isolated from different sources, expanded in culture, and have been shown to be safe in numerous clinical applications.
[Cell Regeneration] |
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| The board of directors of Grayson-Jockey Club Research Foundation announced that it has authorized expenditure of $1,498,077 to fund 12 new projects and nine continuing projects at 13 universities as well as two career development awards.
[Grayson-Jockey Club Research Foundation (Past The Wire)] |
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| April 17 – 19, 2023
Lund, Sweden |
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| | Khalifa University – Abu Dhabi, United Arab Emirates |
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| | STEMCELL Technologies, Inc. – Cambridge, England, United Kingdom |
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| | Fred Hutchinson Cancer Center – Seattle, Washington, United States |
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| | University of Florida – Gainesville, Florida, United States |
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| | Ottawa Hospital Research Institute – Ottawa, Ontario, Canada |
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