 | | Vol. 15.06 – 21 February, 2023 |
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| The authors showed that allogeneic induced pluripotent stem cell-derived cartilage organoids survived and integrated as well as were remodeled as articular cartilage in a primate model of chondral defects in the knee joints.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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Investigators showed that nanotopography could control the immunomodulatory capacity of MSCs through decreased intracellular tension and increasing oxidative glycolysis.
[Nature Communications] |
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| The authors discovered that Fibulin2 expression was upregulated in infected bone tissues and that bone marrow MSCs were the source of infection-induced Fibulin2.
[Experimental & Molecular Medicine] |
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| Investigators demonstrated that methyltransferase-like 16 (METTL16) negatively regulated MCP1 expression in MSCs through m6A modification.
[JCI Insight] |
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| Scientists found that Chidamide, a selective histone deacetylases inhibitor, exhibited remarkably suppressive effect on the in vitro induced adipogenic differentiation of bone marrow-MSCs.
[iScience] |
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| | Investigators researched activating transcription factor-2, a cAMP-response element binding protein, played a crucial role in maintaining the level and activity of Glutathione in human MSCs by crosstalking with nuclear factor erythroid-2 like-2, a well-known master regulator of cellular redox homeostasis.
[Experimental & Molecular Medicine] |
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| Researchers investigated the efficacy of treatment with conditioned medium derived from stem cells from human exfoliated deciduous teeth in a mouse radiation-induced xerostomia model.
[Scientific Reports] |
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| The authors isolated extracellular vesicles from rat MSCs and aimed to delineate their functions and molecular mechanisms in early brain injury following subarachnoid hemorrhage.
[Cell And Tissue Research] |
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| Investigators explored the effect of pro-angiogenic growth factors F-enriched adipose tissue-derived-MSC secretome for accelerating wound angiogenesis and repair in acute large area full thickness excision rabbit wound model.
[3 Biotech] |
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| The authors unify the follicular and non-follicular, non-endothelial stroma of tumours under the ‘peripheral adaptive immune mesenchyme’ framework and position subsets of cancer-associated fibroblasts as direct positive regulators of the adaptive immune system.
[Nature Reviews Cancer] |
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| Even though most studies use the International Society for Cell Therapy criteria, most publications in adult tissues don’t evaluate the characteristics that establish a stem cell, which will be necessary to distinguish between a stem cell and progenitor populations.
[Heliyon] |
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| The FDA will soon require researchers and companies seeking approval for late-stage clinical trials to submit a plan for ensuring diversity among trial participants.
[Nature News] |
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| April 16 – 19, 2023
Snowbird, Utah, United States |
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| | National University of Singapore – Singapore, Singapore |
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| | Harvard Medical School – Boston, Massachusetts, United States |
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| | Khalifa University – Abu Dhabi, United Arab Emirates |
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| | STEMCELL Technologies, Inc. – Cambridge, England, United Kingdom |
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| | Fred Hutchinson Cancer Center – Seattle, Washington, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
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