 | | Vol. 15.37 – 19 September, 2023 |
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| Investigators demonstrated that surface engineering of MSCs with polyvalent antibodies could effectively improve the targeting efficiency of MSCs to diseased tissue.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The effects of human umbilical cord-MSC-derived exosomes on inflammatory cytokine expression, oxidative stress, and microglia polarization were studied by immunofluorescence and western blotting.
[CNS Neuroscience & Therapeutics] |
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| Scientists observed down-regulation of circ_0000888 and pleiotrophin, as well as up-regulation of miR-338-3p in congenital pseudarthrosis of the tibia derived periosteal MSCs.
[iScience] |
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| Researchers examined the biological effect of prominin2 in vitro and in vivo by using experiments including cell proliferation assay, iron assay, reactive oxygen species examination, malondialdehyde assay, and glutathione examination.
[American Journal Of Physiology-Cell Physiology] |
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| TRAIL receptor-Death receptor 4 (DR4), DR5, and lymphocyte function-associated antigen 1 ligand-intercellular adhesion molecule-1 were upregulated in IL-1β-stimulated human fibroblast-like synoviocytes-rheumatoid arthritis.
[Scientific Reports] |
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| The authors investigated how different surface properties induced by either coating deposition or biomolecules immobilization onto nanofibers could affect bone marrow-derived MSCs chondro-inductive behavior.
[Journal of Biomedical Materials Research Part A] |
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| Rabies virus glycoprotein (RVG)-Lamp2b and/or Netrin-1 were overexpressed in human umbilical cord MSCs to obtain exosomes modified with RVG-Lamp2b and/or loaded with Netrin-1.
[Tissue and Cell] |
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| The exosomes were isolated from the supernatant of MSCs pretreated with lipopolysaccharide (LPS). LPS pre-Exo and rapamycin were injected via the tail vein into C57BL/6 mice allografted with BALB/c skin; graft survival was observed and evaluated.
[Journal of Nanobiotechnology] |
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| Scientists found that MSCs confer breast cancer resistance to doxorubicin by diminishing its intratumoral accumulation. Hyaluronan, a major extracellular matrix product of MSCs, was found to mediate the chemoresistant effect.
[Oncogene] |
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| Researchers assessed the influence of bone marrow-derived MSCs on the nephrotoxicity induced by fractionated doses of gamma irradiation and the co-therapy of levetiracetam and oxcarbazepine in male rats.
[Cell Biochemistry and Function] |
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| The authors highlight recent progress in the field of MSC-biomaterial therapies with a focus on the most commonly used biomaterials, classified based on their source, including natural biomaterials, synthetic biomaterials, and the combination of natural and synthetic biomaterials.
[Bioengineering & Translational Medicine] |
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| Scientists review the current knowledge on the mechanisms of action of stromal vascular fraction and hypothesize on how it could potentially respond to some of the unmet treatment needs of refractory myositis.
[Cell Death Discovery] |
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| University of Birmingham Enterprise announced the launch of the Birmingham Dental and Biomaterials Testing Service, to provide consultancy and a comprehensive materials testing service for dental and biomaterial manufacturers.
[University of Birmingham] |
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| October 25 – 28, 2023
London, England, United Kingdom |
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| | University of Maryland – College Park, Maryland, United States |
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| | National Cancer Centre Singapore – Singapore, Singapore |
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| | Chinese Academy of Sciences – Shanghai, China |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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