|
|
Vol. 15.38 – 26 September, 2023
|
|
|
|
|
|
|
|
Scientists showed that the ability of SS18-SSX to occupy H2AK119ub1-rich regions was an intrinsic property of its SSX C terminus, which could be exploited by fusion to transcriptional regulators beyond SS18.
[Nature Structural & Molecular Biology]
|
|
|
|
|
|
PUBLICATIONSRanked by the impact factor of the journal
|
|
|
|
|
|
|
|
The authors adapted a previously described engineered bone marrow construct for use as a three-dimensional platform to study how microenvironmental and immune factors affect osteosarcoma tumor progression.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
|
|
|
|
|
|
To achieve mass production and quality control on stem cells and their exosomes, transfecting umbilical cord MSC (UCMSC) with lentivirus overexpressing human telomerase reverse transcriptase (hTERT) gene, the hTERT-UCMSC was constructed as an immortalized MSC cell line.
[Journal of Tissue Engineering]
|
|
|
|
|
|
Investigators explored the role of δ-Tocotrienol in bone marrow-derived MSC ability of wound healing. Transcriptome and single-cell analysis were used to explore the genes and pathways related to ferroptosis in wound tissues.
[Cell Death Discovery]
|
|
|
|
|
|
Researchers comprehensively explored the potential of various types of stem cells from oral cavity as promising therapeutic options in retinal regeneration.
[Stem Cell Reviews And Reports]
|
|
|
|
|
|
The authors demonstrated that cellular heterogeneity could be highly dynamic and dependent on the micromechanical properties of the substrate.
[Scientific Reports]
|
|
|
|
|
|
Using flow cytometry, adipose tissue-derived MSCs were identified, verified, and their conditioned media was used to treat U87 cells. Through RT-qPCR, scratch assay, and apoptosis analysis, scientists evaluated gene expression, cell migration, and apoptosis in U87 cells.
[Tissue and Cell]
|
|
|
|
|
|
|
|
Investigators characterized creeping fat as pro-adipogenic and pro-fibrotic. Lipidomics analysis of Crohn’s disease patients and healthy controls revealed abnormal lipid metabolism in creeping fat.
[Nature Communications]
|
|
|
|
|
|
Scientists investigated the efficacy of human MSCs in high vs low human macrophage migration inhibitory factor (hMIF) environments and the impact of MIF pre-licensing of MSCs using humanized MIF mice in a clinically relevant house dust mite model of allergic asthma.
[Molecular Therapy]
|
|
|
|
|
|
Therapeutic effects of MSCs/MSC-extracellular vesicles in pristane-induced diffuse pulmonary hemorrhage (DPH) mice were evaluated via pulmonary function testing and histopathology. Transcriptome sequencing analyzed differentially expressed genes in control, DPH, and MSC groups.
[Biotechnology Journal]
|
|
|
|
|
|
The authors co-transplanted bone marrow MSCs with Sertoli cell–conditioned medium into the testis of azoospermic mice.
[Reproductive Sciences]
|
|
|
|
|
|
The exosomes (Exos) were extracted by ultracentrifugation and tetramethylpyrazine was loaded into the Exos by electroporation.
[Journal Of Stroke & Cerebrovascular Diseases]
|
|
|
|
|
|
|
|
|
|
The authors consider the existing evidence regarding the contribution of extracellular matrix-induced intracellular signaling pathways into the regulation of stem cell differentiation, focusing on MSCs as well-studied type of postnatal stem cells totally depended on signals from ECM.
[Cell Communication and Signaling]
|
|
|
|
|
|
|
|
Seven members of the UBC Faculty of Medicine are among 48 new Fellows elected into the Canadian Academy of Health Sciences for 2023.
[UBC Faculty of Medicine]
|
|
|
|
|
|
|
|
November 1 – 3, 2023
Virtual
|
|
|
|
|
|
|
|
|
|
|
National University of Singapore – Singapore, Singapore
|
|
|
|
|
|
|
University of Maryland – College Park, Maryland, United States
|
|
|
|
|
|
|
National Cancer Centre Singapore – Singapore, Singapore
|
|
|
|
|
|
|
Cedars-Sinai – Los Angeles, California, United States
|
|
|
|
|
|
|
Cedars-Sinai – Los Angeles, California, United States
|
|
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News