 | | Vol. 16.01 – 16 January, 2024 |
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| Researchers engineered a scaffold-free MSC sheet with an inherent ability to migrate into the infarcted myocardium, a strategy enabled by actively establishing a sustained intracellular hypoxic environment through the endocytosis of our FDA-approved ferumoxytol.
[ACS Nano] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists identified zonula occludens-1 (ZO-1) as a specific intrinsic molecule that played a vital role in mediating the collective migration of MSCs towards breast tumor cells and transforming growth factor beta, which was a crucial factor secreted by breast tumor cells.
[Cell Death Discovery] |
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| Glucose uptake and lactate production assays were used to evaluate the importance of B7H3 expression in gastric cancer MSCs-treated gastric cancer cells. The therapeutic efficacy of oxaliplatin and paclitaxel was determined using CCK-8 and colony formation assays.
[Journal Of Cellular Biochemistry] |
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| Investigators focused on analyzing the role of umbilical cord MSC-derived exosomes in reducing lipopolysaccharide-induced acute lung injury and investigated the mechanism involved.
[Journal Of Cellular Biochemistry] |
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| Scientists investigated the effects of microRNA-124a on the differentiation of bone marrow MSCs and its underlying mechanism.
[Journal of Receptors and Signal Transduction] |
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| Umbilical cord MSC conditioned medium produced positive effects on TGF-β induced intrauterine adhesion cell model.
[Biology Open] |
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| Investigators evaluated cell-specific changes in MAPKAPK2 (MK2) activity between predominantly inflammatory Crohn’s disease (CD) versus CD with fibrotic complication and defined the role of stromal cell-specific MK2 activation in CD-associated. CD tissue-derived MSCs and conditional KO mice were used.
[Journal of Crohn’s and Colitis] |
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| Researchers investigated the potential of bone marrow-derived MSCs modified with XIST lentiviral vector to modulate macrophage polarization and affect neural stem cell microenvironment reconstruction following spinal cord injury.
[Journal Of Tissue Engineering] |
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| Scientists performed a pilot clinical study to determine whether bone marrow-derived MSCs from head and neck cancer patients could be used for the treatment of RT-induced salivary dysfunction.
[Radiotherapy And Oncology] |
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| The authors investigate the intertwine between the mechanisms of action of intervertebral disc (IVD) components and the therapeutic potential of MSCs, exploring their characteristics, and how to optimize their use and establish them safely in distinct settings for low back pain treatment.
[Cell Regeneration] |
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| Elevai Labs, Inc. announced it has signed an exclusive, worldwide manufacturing and processing technology licensing agreement with INmune Bio that enables Elevai to manufacture human umbilical cord-derived MSCs (hucMSCs) at a lower cost to Elevai than purchasing hucMSCs outright.
[Elevai Lab, Inc.] |
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| February 14 – 18, 2024
Cancun, Mexico |
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| | Karolinska Institutet – Solna, Sweden |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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| | Francis Crick Institute – London, England, United Kingdom |
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| | University of Texas Health Science Center at San Antonio – San Antonio, Texas, United States |
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| | Institut Pasteur – Paris, France |
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