 | | Vol. 16.06 – 20 February, 2024 |
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| Scientists used chitin-based nanoscaffolds to establish a novel MSC three-dimensional (3D) culture. They compared 2D and 3D cultured human umbilical cord-MSCs, including differentiation assays, cell markers, proliferation, and angiogenesis.
[Bioactive Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers reported the design of a microfluidic device that was capable of single-cell encapsulation within PEG norbornene hydrogels on-chip. Singly encapsulated MSCs had elevated expression levels in genes that code anti-inflammatory cytokines thus enhancing the secretion of proteins of interest.
[Advanced Healthcare Materials] |
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| Using a layer-by-layer self-assembly technique, investigators fabricated alginate and gelatin microgel to encapsulate individual MSC for treating disc degeneration.
[Research] |
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| Scientists analyzed by RNA sequencing Lin–SCA1+ MSCs enriched from bone marrow (BM) by immunodepletion and after subsequent culture expansion and Lin−LEPR+ MSCs sorted directly from BM.
[Cytotherapy] |
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| Investigators identified potential biomarkers from osteoclast progenitors, specifically peripheral blood monocytes on predicting the osteoporotic phenotype. Its osteogenesis, migration, and proliferation abilities in bone MSCs were validated.
[Aging] |
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| Scientists investigated whether erythropoietin (EPO) can treat pulmonary arterial hypertension in rats by regulating the differentiation and homing of bone marrow MSCs through Notch1/Jagged signaling pathway.
[Heliyon] |
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| Investigators proposed that MSC-extracellular vesicles (EVs) could be combined with histone deacetylase 7-derived 7-amino-acid peptide (7A) to greatly promote diabetic wound healing. The combination of EVs and 7A significantly improved the migration and proliferation of skin fibroblasts.
[Biomaterials Science] |
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| Researchers investigated the potential roles of saroglitazar and/or breast milk mesenchymal stem cells in pumonary fibrosis and to spot their underlying protective mechanisms.
[Naunyn-Schmiedebergs Archives Of Pharmacology] |
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| Scientists explored the influence of the periostin/bone morphogenetic protein 1 axis on the growth and osteogenic maturation of suture MSCs, which were pivotal in suture homeostasis.
[Journal Of Orthopaedic Surgery And Research] |
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| The authors summarize the most recent literatures on how preconditioning of MSCs influences the regenerative potential of their exosomes in tissue repair and provides new insights into the therapeutic application of exosomes derived from MSCs.
[Regenerative Therapy] |
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| While training for the upcoming mission was underway, two NASA Flight Engineers, Jasmin Moghbeli and Loral O’Hara, focused a majority of their day on the Mesenchymal Stem Cells in Microgravity Induced Bone Loss investigation.
[NASA Space Station] |
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| The University of Liverpool has launched a new spin-out company, TrophiCell, that has developed a revolutionary approach to harness the therapeutic potential of adult MSCs.
[University of Liverpool] |
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| March 11 – 13, 2024
Lisbon, Portugal |
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| | University of Southern California – Los Angeles, California, United States |
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| | UC Davis – Davis, California, United States |
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| | BC Provincial Health Services Authority – Vancouver, British Columbia, Canada/p> |
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| | Universitätsklinikum Ulm – Ulm, Germany |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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