| Vol. 16.10 – 19 March, 2024 |
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| Scientists showed in murine mesenchymal progenitor cells that had Atrx deficiency aberrantly activated mesenchymal differentiation programs. [Nucleic Acids Research] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| 5% liver fibrosis serum was used to induce the therapeutic phenotype of MSCs, and a fluid bioreactor carrying a co-culture system of hepatocytes and MSCs was constructed to produce the therapeutic medium. [Biofabrication] |
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| To enhance its osteogenic activity while reducing dosage and administration frequency, investigators developed a novel long-acting BMP4 delivery system using poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) (PBVHx) nanoparticles with soybean lecithin-modified BMP4. [International Journal Of Biological Macromolecules] |
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| The authors attempted to increase the amount of single cell RNA sequence data for osteoblasts and osteocytes, to compare cells from the periosteum to those inside bone, and to clarify the major categories of cell types associated with murine bone. [Journal Of Biological Chemistry] |
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| Chromatin immunoprecipitation-sequencing analysis revealed that C-FOS bound mainly to the promoters of WNT1, miR-30a, and ANAPC7 and regulates their expression during mitotic clonal expansion. [Journal Of Cellular Biochemistry] |
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| Researchers explored the potential of promoting repair in the injured spinal cord by delivering bone MSCs that had internalized nanoparticles preloaded with azithromycin. [ACS Nano] |
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| The authors investigated if osteopontin modulated cell senescence and bone regenerative function in human adipose-derived mesenchymal stem cells, and to determine the underlying mechanisms. [Stem Cell Reviews And Reports] |
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| Scientists demonstrated that transient receptor potential cation channel subfamily V member 4 (TRPV4), a mechanosensitive, thermogated, and nonselective cation channel, was endogenously present in the MSCs. [ACS Biomaterials Science & Engineering] |
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| Researchers established the intrauterine adhesion model of the Sprague–Dawley rat using lipopolysaccharide infection and mechanical scratching. Phosphate-buffered saline, bone marrow (B)MSCs alone, and BMSCs combined with electroacupuncture were randomly administered to the rats. [Reproductive Sciences] |
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| Investigators summarize the recent advances in miRNAs of MSC-derived exosomes (EXOs) as a treatment for retinal degeneration, discussing the strategies and methods for engineering therapeutic MSC-EXOs. [Biomedicine & Pharmacotherapy] |
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| Scientists summarize the advantages of three dimensionally-cultured exosomes and introduce the 3D culture system and methods of exosome isolation, providing scientific strategies for the diagnosis, treatment, and prognosis of a wide variety of diseases. [Tissue Engineering Part B-Reviews] |
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| The Korea Health Industry Development Institute (KHIDI) has inked a memorandum of understanding with the Medical Research Council, part of the UK’s Research and Innovation (UKRI). [Korea Biomedical Review] |
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| April 24 – 26, 2024 Vienna, Austria |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| University of California, Davis – Sacramento, California, United States |
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| King’s College London – London, England, United Kingdom |
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| University of Sydney – Sydney, Australia |
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| UC Davis – Davis, California, United States |
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