 | | Vol. 16.13 – 9 April, 2024 |
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| Investigators constructed regulatory T cell-derived exosomes for the treatment of fracture. The obtained exosomes displayed a spheroid shape with a hydrated particle size of approximately 130 nm.
[Journal Of Controlled Release] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers explored the role of miR-140-5p delivered by MSC-extracellular vesicles in mitigating brain damage following subarachnoid hemorrhage (SAH). Serum from SAH patients and healthy individuals was analyzed for miR-140-5p and cAMP levels.
[Molecular Neurobiology] |
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| Exosomes derived from bone marrow MSCs were isolated by ultracentrifugation and characterized using transmission electron microscopy and nanoflow cytometry.
[Stem Cells And Development] |
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| In vitro, adipose stem cell-derived exosomes significantly enhanced proliferation and migration of rat skin fibroblasts while reducing the expression of TGF-β1 and α-SMA.
[Molecular And Cellular Endocrinology] |
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| Two common sources of MSCs, umbilical cord-derived MSCs and adipose tissue-derived MSCs, were orthotopically transplanted into a mouse model of ovarian aging to evaluate their therapeutic effects.
[Stem Cell Research & Therapy] |
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| The tibial denervation model was used and the denervated tibia exhibited significantly lower mass as compared to sham operated bones.
[Journal of Cellular and Molecular Medicine] |
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| Investigators successfully prepared cell membrane vesicles from BMSCs and endothelial cells. The results showed that BMSC-derived cell membrane vesicles possessed membrane receptors involved in juxtacrine signaling and growth factors derived from their parental cells.
[Scientific Reports] |
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| The authors investigated the expression of acyl-CoA synthetase long-chain family member 4 (ACSL4) in osteosarcoma (OS) tissues using immunohistochemistry staining staining of a human tissue microarray and in OS cells by qPCR assay.
[Molecular And Cellular Biochemistry] |
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| MSCs transplantation therapy is widely used in the fields of tissue regeneration and repair, and treatment of inflammatory diseases. Scientists summarize the current evidence on the regulation of apoptosis by MSCs.
[Cell Death & Disease] |
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| Literature was obtained from databases PubMed and Web of Science. Key words were chosen for COVID-19, acute respiratory syndrome coronavirus 2, MSCs, stem cell therapy, and therapeutic mechanism.
[Journal Of Tissue Engineering And Regenerative Medicine] |
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| Charles River Laboratories International, Inc. announced a plasmid DNA contract development and manufacturing organization collaboration with Axovia Therapeutics Ltd.
[Charles River Laboratories International, Inc. (BusinessWire, Inc.)] |
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| May 9 – 12, 2024
Melbourne, Australia |
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| | University of Wisconsin-Madison – Madison, Wisconsin, United States |
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| | Cellistic – Mont-Saint-Guibert, Belgium |
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| | The University of Hong Kong – Hong Kong, Hong Kong |
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| | University of Veterinary Medicine Vienna – Vienna, Austria |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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