 | | Vol. 16.16 – 30 April, 2024 |
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| By combining epigenomics, transcriptomics, and in-pouch marsupial transgenics, scientists showed that Emx2 was a critical upstream regulator of patagium development.
[Nature] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators compared perinatal and adult bone marrow MSCs. MSCs exhibited enrichment in genes mediating m6A mRNA methylation at the perinatal stage and downregulated the expression of Mettl3 shortly after birth.
[Cell] |
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| Bottlebrush polymers were synthesized and crosslinked to form poly(ethylene glycol)-based hydrogels and used to study how strain-stiffening behavior affects human MSCs.
[Advanced Materials] |
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| Single cell human small intestine organoids were embedded in Matrigel, grown for five days and treated with busulfan for 48 hours.
[Stem Cell Research & Therapy] |
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| Recombinant human bone morphogenetic protein 2 (rhBMP-2) and human bone marrow MSCs were tested in an in vivo subcutaneous implantation model to assess their ability to form mature bone and undergo multilineage differentiation.
[Stem Cell Research & Therapy] |
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| The expression of homeobox gene B5 (HOXB5) in human osteosarcoma tissues and its correlation with clinical indicators were investigated using bioinformatics analysis and immunohistochemical labelling.
[Heliyon] |
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| Wharton’s Jelly-derived-MSCs were isolated from human umbilical cord. The cells were incubated according to the standard culture conditions and characterized by flow cytometry.
[Molecular Biology Reports] |
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| Investigators explored the possibilities of ependymal repair in germinal matrix hemorrhage/posthemorrhagic hydrocephalus using a combination of neural stem cells, ependymal progenitors, and mesenchymal stem cells.
[Stroke] |
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| Scientists investigated how extracellular matrix composition modulated CD8+ T cell function in undifferentiated pleomorphic sarcoma, an immunologically active desmoplastic tumor.
[European Journal Of Clinical Investigation] |
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| The authors summarize published studies demonstrating donor-sex-related MSC heterogeneity and emphasize the importance of disclosing donor sex as a key factor affecting MSC potency in cell therapy.
[Stem Cell Research & Therapy] |
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| Replay and The University of Texas MD Anderson Cancer Center announced that the FDA has issued a ‘safe to proceed’ for the Investigational New Drug (IND) application for PRAME TCR/IL-15 NK (SY-307) for relapsed/refractory myeloid malignancies.
[Replay] |
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| May 20, 2024
New York, New York, United States & Online |
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| | Institut Pasteur – Paris, France |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | City of Hope – Duarte, California, United States |
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| | University of Dundee – Dundee, Scotland, United Kingdom |
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| | University of Oregon – Eugene, Oregon, United States |
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