Mesenchymal Cell News Volume 2.37 | Sep 21 2010

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    Mesenchymal Cell News 2.37, September 21, 2010.
    In this issue: Science News  |  Current Publications  |  Industry News  |  Policy News  |  EventsSubscribe  |  Unsubscribe

    TOP STORY

    Keratinocyte Proximity and Contact Can Play a Significant Role in Determining Mesenchymal Stem Cell Fate in Human Tissue
    Researchers show how the epidermal keratinocyte can direct human mesenchymal stem cell differentiation selectively. [FASEB J]

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    SCIENCE NEWS

    Fat Stem Cells Safe for Breast Reconstruction when Cancer is Dormant, Says Pitt Team
    Fat-derived stem cells can be safely used to aid reconstruction of breast tissue after mastectomy as long as there is no evidence of active cancer, according to researchers. [Press release from the University of Pittsburgh Schools of the Health Sciences discussing online prepublication in Tissue Engineering Part A]

    Ovary Stem Cell Treatment Could ‘Help Early Menopause Women’
    Researchers in Cairo, Egypt, have come up with a way of restoring the ability of ovaries to produce eggs using cells developed in the lab. [International Federation of Gynecology and Obstetrics Press Release]

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    CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal)

    The Growth of Brain Tumors can be Suppressed by Multiple Transplantation of Mesenchymal Stem Cells Expressing Cytosine Deaminase
    Here, researchers showed a potential ex vivo therapy that used mesenchymal stem cells as cellular vehicles to deliver a bacterial suicide gene, cytosine deaminase to brain tumors. [Int J Cancer]

    Polyhydroxybutyrate and its Copolymer with Polyhydroxyvalerate as Biomaterials: Influence on Progression of Stem Cell Cycle
    This study investigated the influence biomaterials, poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate), exerted on cell cycle progression of olfactory ensheathing cells and mesenchymal stem cells commonly used in the engineering of nerve and bone tissues. [Biomacromolecules]

    Low Doses of BMP4 Increases the Survival of Human Adipose-Derived Stem Cells Maintaining their Stemness and Multipotency
    The results support BMP4 as a promising factor for expanding human adipose tissue-derived mesenchymal stem cells while maintaining their properties of stemness and multipotency. [Stem Cells Dev]

    Inflammatory Conditions Affect Gene Expression and Function of Human Adipose Tissue-Derived Mesenchymal Stem Cells
    Adipose tissue-derived mesenchymal stem cells were cultured with alloactivated peripheral blood mononuclear cells (mixed lymphocyte reaction), with proinflammatory cytokines [interferon (IFN)-gamma, tumour necrosis factor (TNF)-alpha and interleukin (IL)-6] or under control conditions, and their full genome expression and function examined. [ Clin Exp Immunol]

    Myogenic Lineage Differentiated Mesenchymal Stem Cells Enhance Recovery from Dextran Sulfate Sodium-Induced Colitis in the Rat
    Researchers investigated the role of transplanted mesenchymal stem cells in the repair phase of dextran sulfate sodium-induced colitis. [J Gastroenterol]

    Zinc Supplementation Results in Improved Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stromal Cells in a Mouse Ischemic Limb Model
    Researchers wanted to determine whether zinc supplementation can inhibit bone marrow-derived mesenchymal stromal cell apoptosis and enhance their tissue regenerative potential in a mouse ischemic hindlimb model. [Cytotherapy]

    Optimization of Culture Conditions for Osteogenically-Induced Mesenchymal Stem Cells in Beta-Tricalcium Phosphate Ceramics with Large Interconnected Channels
    The aim of this study was to optimize culture conditions for human mesenchymal stem cells in beta-tricalcium phosphate ceramics with large interconnected channels. [J Tissue Eng Regen Med]

    INDUSTRY NEWS

    Mesoblast Featured at International Scientific Conferences
    Clinical advances by regenerative medicine company Mesoblast Limited were featured prominently at the 39th annual meeting of the International Society for Experimental Hematology (ISEH) and the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Asia Pacific meeting. [Mesoblast Limited Press Release]

    POLICY NEWS

    NHGRI Funds Development of Third Generation DNA Sequencing Technologies
    More than $18 million in grants to spur the development of a third generation of DNA sequencing technologies was announced by the National Human Genome Research Institute. [National Institutes of Health, United States]

    Innovative Emerging Molecular Analysis Technologies (SBIR R43/R44) (RFA-CA-10-013) [National Institutes of Health, United States]

    Prospective Grant of Exclusive License: The Development of Immunotoxins/Targeted Toxins for the Treatment of Human Cancer (FR Doc. 2010-22844) [National Institutes of Health, United States]

    National Human Genome Research Institute; Notice of Closed Meeting (FR Doc. 2010-23027) [National Institutes of Health, United States]

    National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-23144) [National Institutes of Health, United States]

    Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-23143) [National Institutes of Health, United States]

    Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-23275) [National Institutes of Health, United States]

    Agenda for the Public Workshop on Cell and Gene Therapy Clinical Trials in Pediatric Populations [Food and Drug Administration, United States]

    EVENTS (Listed by Date)

    2010 World Stem Cell Summit
    October 4-6, 2010
    Detroit, United States

    5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010
    October 5-7, 2010
    Hannover, Germany

    17th Annual Meeting German Society for Gene Therapy (DG-GT e.V.)
    October 6-9, 2010
    Munich, Germany

    bone-tec 2010 – International Bone-Tissue Engineering Congress
    October 7-10, 2010
    Hannover, Germany

    NEW Functional Stem Cell and Regeneration
    October 9-10, 2010
    Kansas City, United States

    The NYSCF Fifth Annual Translational Stem Cell Research Conference
    October 12-13, 2010
    New York, United States

    NEW 4th International Symposium Stem Cells, Development and Regulation
    October 12-14, 2010
    Amsterdam, Netherlands

    International Federation of Adipose Therapeutics & Science (IFATS) 2010 Conference
    October 22-24, 2010
    Dallas, United States

    2010 American Society for Matrix Biology (ASMB) Meeting
    October 24-27, 2010
    Charleston, United States

    NEW FDA Public Workshop on Cell and Gene Therapy Clinical Trials in Pediatric Populations
    November 2, 2010
    North Bethesda, United States

    Stem Cell Society Singapore Symposium 2010
    November 2-3, 2010
    Singapore

    NEW Select Biosciences 2nd International Forum on Stem Cells (2010 IFSC)
    November 12-13, 2010
    Tianjin, China

    NEW The 16th International Conference of the International Society of Differentiation: From Stem Cells to Organisms
    November 15-18, 2010
    Nara, Japan

    NEW Stem Cell Network’s 10th Annual Scientific Meeting
    November 22-24, 2010
    Calgary, Alberta

    52nd American Society of Hematology (ASH) Annual Meeting and Exposition
    December 4-7, 2010
    Orlando, United States

    Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference
    December 5-8, 2010
    Orlando, United States

    Epithelial Plasticity and Epithelial to Mesenchymal Transition (A8)
    January 21-26, 2011
    Vancouver, Canada

    Phacilitate 7th Annual Cell & Gene Therapy Forum 2011
    January 24-26, 2011
    Washington DC, United States

    Stem Cells in Development, Tissue Homeostasis and Disease
    January 30-February 4, 2011
    Santa Fe, United States

    NEW American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer
    March 3-6, 2011
    Vancouver, Canada

    Stem Cells, Cancer and Metastasis (C4)
    March 6-11, 2011
    Keystone, United States

    Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference
    June 7-10, 2011
    Granada, Spain

    NEW International Society for Stem Cell Research (ISSCR) 9th Annual Meeting
    June 15-18, 2011
    Toronto, Canada

    Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.


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