CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Glucocerebrosidase Gene-Deficient Mouse Recapitulates Gaucher Disease Displaying Cellular and Molecular Dysregulation Beyond the Macrophage Researchers conditionally deleted the glucocerebrosidase gene in hematopoietic and mesenchymal cell lineages using an Mx1 promoter. [Proc Natl Acad Sci USA] Mesenchymal Stem Cells or Cardiac Progenitors for Cardiac Repair? A Comparative Study In this study, researchers performed a comparative study between human mesenchymal stem cells, purified c-kit+ cardiac stem cells, and cardiosphere-derived cells. [Cell Mol Life Sci] Matrix Stiffness Regulation of Integrin-Mediated Mechanotransduction During Osteogenic Differentiation of Human Mesenchymal Stem Cells Results provides evidence that matrix rigidity affects the osteogenic outcome of mesenchymal stem cells through mechano-transduction events that are mediated by alpha2 integrin. [J Bone Miner Res] New Strategies for Anterior Cruciate Ligament Partial Rupture Using Bone Marrow Transplantation in Rats The purpose of this study was to compare anterior cruciate ligament regeneration between animal groups subjected to intra-articular injection of fresh whole bone marrow cells, cultured mesenchymal stem cells, or saline. [Stem Cells Dev] Regulation of Human Mesenchymal Stem Cell Functions by an Autocrine Loop Involving NAD+ Release and P2Y11-Mediated Signaling In several cell types, a regulated efflux of NAD+ across Connexin 43 hemichannels (Cx43 HC) can occur and extracellular NAD+ (NAD+e) affects cell-specific functions. Researchers studied the capability of bone marrow-derived human mesenchymal stem cells to release intracellular NAD+ through Cx43-HC. [Stem Cells Dev] Reduced Satellite Cell Numbers and Myogenic Capacity in Aging Can Be Alleviated by Endurance Exercise Here, researchers focused on characterizing the effect of moderate-intensity endurance exercise on satellite cell, as possible means to attenuate adverse effects of aging. [PLoS ONE] Correlation Between Compositional and Mechanical Properties of Human Mesenchymal Stem Cell-Collagen Microspheres During Chondrogenic Differentiation In this study, a novel human Mesenchymal stem cell-collagen microsphere system was used to study the compositional mechanical relationship during in vitro chondrogenic differentiation using histological and biochemical methods and a microplate compression assay. [Tissue Eng Part A] A Microfabricated Scaffold Induces the Spheroid Formation of Human Bone Marrow-Derived Mesenchymal Progenitor Cells and Promotes Efficient Adipogenic Differentiation Here, researchers report the highly efficient in vitro differentiation of human bone marrow-derived mesenchymal stem/progenitor cells using a novel nanotechnology-based culture plate, nanoculture plate (R). [Tissue Eng Part A] Synergistic Angiogenesis Promoting Effects of Extracellular Matrix Scaffolds and Adipose-Derived Stem Cells During Wound Repair The aim of this study was to promote the vascularization capacities of scaffolds by seeding adipose-derived stem cells (ADSCs) on them and to compare the vascularization capacities of different scaffolds seeded with ADSCs. [Tissue Eng Part A]
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POLICY NEWS NIH Recovery Act Awards Enable Crucial Health Research Technologies Thanks to the Recovery Act, more health scientists now will have access to state-of-the-art devices, the National Institutes of Health announced. Through its National Center for Research Resources, NIH has awarded $300 million in shared instrumentation grants. [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26362) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26363) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26317) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26497) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26499) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-26028) [National Institutes of Health, United States] National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-26702) [National Institutes of Health, United States] National Cancer Institute; Notice of Closed Meetings (FR Doc. 2010-26706) [National Institutes of Health, United States] National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-26390) [National Institutes of Health, United States] Office of the Director, National Institutes of Health; Notice of Meeting (FR Doc. 2010-26036) [National Institutes of Health, United States] Export of Human Blood/Tissue and Related Materials [Therapeutic Goods Administration, Australia]
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EVENTS (Listed by Date) Queen Mary University of London: 5th UK Cancer Stem Cell Symposium November 2, 2010 London, United Kingdom Stem Cell Society Singapore Symposium 2010: Translating Science to Therapy November 2-3, 2010 Singapore National Cancer Research Institute (NCRI) Conference 2010 November 7-10, 2010 Liverpool, United Kingdom 9th Annual American Association for Cancer Research (AACR) International Conference: Frontiers in Cancer Prevention Research November 7-10, 2010 Philadelphia, United States NEW Third Annual Research Experience of Stem Cells in European (RESCUE) Society Conference November 8-9, 2010 Oxford, United Kingdom Select Biosciences 2nd International Forum on Stem Cells (2010 IFSC) November 12-13, 2010 Tianjin, China The 16th International Conference of the International Society of Differentiation: From Stem Cells to Organisms November 15-18, 2010 Nara, Japan 22nd European Organization for Research and Treatment of Cancer (EORTC)-National Cancer Institute (NCI)-American Association for Cancer Research (AACR) Symposium: Molecular Targets and Cancer Therapeutics November 16-19, 2010 Berlin, Germany Translational Excellence in Regenerative Medicine (TeRM) – Biophysical Stimuli and Mass Transport for Tissue Development November 18-19, 2010 Lattrop, The Netherlands Stem Cell Network’s 10th Annual Scientific Meeting November 22-24, 2010 Calgary, Canada First Berlin-Brandenburg School for Regenerative Therapies (BSRT) PhD Symposium December 1-3, 2010 Berlin, Germany 52nd American Society of Hematology (ASH) Annual Meeting and Exposition December 4-7, 2010 Orlando, United States Tissue Engineering & Regenerative Medicine International Society – North America (TERMIS-NA) 2010 Annual Conference December 5-8, 2010 Orlando, United States 5th Annual Stem Cell Meeting on the Mesa December 7, 2010 La Jolla, United States The American Society for Cell Biology 50th Annual Meeting December 11-15, 2010 Philadelphia, United States NEW Pharmacology in Stem Cells Research and Regenerative Medicine December 17, 2010 London, United Kingdom Keystone Symposia: Epithelial Plasticity and Epithelial to Mesenchymal Transition January 21-26, 2011 Vancouver, Canada 5th Annual Stem Cells and Regenerative Medicine World Congress January 24-25, 2011 San Diego, United States Phacilitate 7th Annual Cell & Gene Therapy Forum 2011 January 24-26, 2011 Washington, D.C., United States Keystone Symposia: Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States NEW 1st Annual Clinical Meeting of the Cell Society February 18-19, 2011 La Jolla, United States American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer March 3-6, 2011 Vancouver, Canada Stem Cells, Cancer and Metastasis (C4) March 6-11, 2011 Dillon, United States NEW United Kingdom National Stem Cell Network 2011 Annual Scientific Conference March 30-April 1, 2011 York, United Kingdom Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference June 7-10, 2011 Granada, Spain International Society for Stem Cell Research (ISSCR) 9th Annual Meeting June 15-18, 2011 Toronto, Canada Tissue Engineering & Regenerative Medicine International Society (TERMIS) 2011 Asia Pacific Meeting (TERMIS AP 2011) August 3-5, 2011 Singapore Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Lab Technologist — Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies) Lab Technologist — Tissue Culture (STEMCELL Technologies) Product Manager — Pluripotent Stem Cells (STEMCELL Technologies) Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Mesenchymal Cell News at no cost. Visit here to post your career opportunities.
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