CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) A Dynamic Notch Injury Response Activates Epicardium and Contributes to Fibrosis Repair Researchers asked whether, as in other tissues of this mouse, enhanced green fluorescent protein localized and functionally tagged adult cardiac tissue progenitors, and, if so, whether this cell-based signal could serve as a quantitative and qualitative biosensor of the injury repair response of the heart. [Circ Res] VEGF-Expressing Human Umbilical Cord Mesenchymal Stem Cells, An Improved Therapy Strategy for Parkinson’s Disease As both vascular endothelial growth factor (VEGF) and human umbilical cord mesenchymal stem cells (HUMSCs) displayed limited neuroprotection, in this study researchers investigated whether HUMSCs combined with VEGF expression could offer enhanced neuroprotection. [Gene Ther] Cartilage Tissue Engineering Using Electrospun PCL Nanofiber Meshes and MSCs Adherent, colony-forming, fibroblastic cells were isolated from human bone marrow aspirates, from patients undergoing knee arthroplasties, and the mesenchymal stem cell (MSC) phenotype characterized by flow cytometry. Afterward, cells were seeded onto electrospun polycaprolactone nanofiber meshes and cultured in a multichamber flow perfusion bioreactor to determine their ability to produce cartilagineous extracellular matrix. [Biomacromolecules] Quantifying Osteogenic Cell Degradation of Silk Biomaterials The degradation of silk protein films by human mesenchymal stem cells, osteoblasts and osteoclasts, cells involved in osteogenic functions in normal and diseased bone, was assessed in vitro. [Biomacromolecules] Enhanced Proliferation and Chondrogenic Differentiation of Human Synovium-Derived Stem Cells Expanded with Basic Fibroblast Growth Factor Basic fibroblast growth factor (bFGF) was reported to augment the differentiation potential of mesenchymal stem cells originating from a variety of sources. In this study, researchers applied various concentrations of bFGF to monolayer cultures of synovium-derived stem cells and evaluated its effects on proliferation and chondrogenesis. [Tissue Eng Part A] Osteogenic Media and rhBMP-2 Induced Differentiation of Umbilical Cord Mesenchymal Stem Cells Encapsulated in Alginate Microbeads and Integrated in an Injectable Calcium Phosphate-Chitosan Fibrous Scaffold The objectives of this study are to: (1) Develop a novel human umbilical cord mesenchymal stem cell (hUCMSC) encapsulating, fiber-reinforced injectable calcium phosphate cement (CPCF) scaffold; (2) investigate the effects of osteogenic media delivery, pre-osteodifferentiation, and BMP-2 delivery on hUCMSC osteodifferentiation inside CPCF for the first time. [Tissue Eng Part A] Fibrocartilage Tissue Engineering: The Role of the Stress Environment on Cell Morphology and Matrix Expression Mesenchymal stromal cells in a three-dimensional culture were exposed to compressive and tensile stresses as a result of an external tensile hydrostatic stress field. [Tissue Eng Part A]
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EVENTS (Listed by Date) Pharmacology in Stem Cells Research and Regenerative Medicine December 17, 2010 London, United Kingdom The 3rd Guangzhou International Conference on Stem Cell Biology and Regenerative Medicine December 17-19, 2010 Guangzhou, China Keystone Symposia: Epithelial Plasticity and Epithelial to Mesenchymal Transition January 21-26, 2011 Vancouver, Canada 5th Annual Stem Cells and Regenerative Medicine World Congress January 24-25, 2011 San Diego, United States Phacilitate 7th Annual Cell & Gene Therapy Forum 2011 January 24-26, 2011 Washington, D.C., United States Keystone Symposia: Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States Stem Cell Research Forum of India 2nd Annual Meeting February 8-11, 2011 Bangalore, India 1st Annual Clinical Meeting of the Cell Society February 18-19, 2011 La Jolla, United States SMi Stem Cells 2011 – Innovation and Commercialisation February 23-24, 2011 London, United Kingdom NEW Cell Culture World Congress 2011 – Optimising Cell Culture Development for Biopharmaceutical, Bioprocessing and Manufacture February 28-March 2, 2011 Munich, Germany 6th Annual Stem Cell Summit March 1, 2011 New York, United States American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer March 3-6, 2011 Vancouver, Canada Keystone Symposia: Stem Cells, Cancer and Metastasis March 6-11, 2011 Dillon, United States NEW PITTCON Conference & Expo 2011 March 13-18, 2011 Atlanta, United States 15th Annual Hilton Head Workshop – Regenerative Medicine, Innovations for Clinical Applications March 16-19, 2011 Hilton Head Island, United States StemCONN 11 March 22, 2011 Farmington, United States United Kingdom National Stem Cell Network 2011 Annual Scientific Conference March 30-April 1, 2011 York, United Kingdom NEW World Stem Cells & Regenerative Medicine Congress 2011 May 9-11, 2011 London, United Kingdom Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference June 7-10, 2011 Granada, Spain International Society for Stem Cell Research (ISSCR) 9th Annual Meeting June 15-18, 2011 Toronto, Canada Tissue Engineering & Regenerative Medicine International Society (TERMIS) 2011 Asia Pacific Meeting (TERMIS AP 2011) August 3-5, 2011 Singapore Adult MSC2011 Innovations in Cell-Based Regenerative Therapies August 22-24, 2011 Cleveland, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Lab Technologist – Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies) Lab Technologist – Tissue Culture (STEMCELL Technologies) Product Manager – Pluripotent Stem Cells (STEMCELL Technologies) Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Mesenchymal Cell News at no cost. Visit here to post your career opportunities.
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