| Current Publications (Ranked by Impact Factor of the Journal) | Effects of Hypoxias and Scaffold Architecture on Rabbit Mesenchymal Stem Cell Differentiation Towards a Nucleus Pulposus-Like Phenotype In this study, three-dimensional nanofibrous poly(l-lactide) scaffolds were seeded with multi-potent rabbit mesenchymal stem cells and the constructs were induced along nucleus pulposus development routes in a hypoxia chamber (2% O2) in the presence of TGF-β1. [Biomaterials] Chondrogenic Potential of Stem Cells Derived from Amniotic Fluid, Adipose Tissue, or Bone Marrow Encapsulated in Fibrin Gels Containing TGF-β3 In this study, several types of human mesenchymal stem cells, derived from bone marrow, adipose tissue, or amniotic fluid, were encapsulated in a fibrin hydrogel mixed with TGF-β3 and then evaluated for their capacity for differentiation in vitro and in vivo. [Biomaterials] Immunological Aspects of Allogeneic and Autologous Mesenchymal Stem Cell Therapies In the present study researchers examined whether natural killer cell-mediated lysis of mesenchymal stem cells could be inhibited by immunosuppressive drugs. [Hum Gene Ther] The Influence of Hypoxia and Fibrinogen Variants on the Expansion and Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In this study, the influence of oxygen tension and naturally occurring fibrinogen variants on adipose tissue-derived mesenchymal stem cell expansion and differentiation were determined. [Tissue Eng Part A] Change in Hepatocyte Growth Factor Concentration Promotes Mesenchymal Stem Cell-Mediated Osteogenic Regeneration This study aimed to determine the mechanisms by which different concentrations of HGF regulate mesenchymal stem cell proliferation and osteogenic differentiation, and validate the mechanism in an animal model of early stage avascular necrosis of femoral head. [J Cell Mol Med] Overexpression of Csx/Nkx2.5 and GATA-4 Enhances the Efficacy of Mesenchymal Stem Cell Transplantation After Myocardial Infarction The aim of the present study was to investigate the effect of transplanting mesenchymal stem cells overexpressing Csx/Nkx2.5 and GATA-4 (MSCs-CG) after myocardial infarction. [Circ J] Scaffold-Free Culture of Mesenchymal Stem Cell Spheroids in Suspension Preserves Multilineage Potential In this study, mesenchymal stem cell spheroids, or “mesenspheres”, of different sizes, were formed using a forced aggregation technique and maintained in suspension culture for extended periods of time thereafter. [Cell Tissue Res] Estrogen and Its Receptor Enhance Mechanobiological Effects in Compressed Bone Mesenchymal Stem Cells To investigate the role of estrogen and its receptors in the mechanobiological effects in bone mesenchymal stem cells, isolated mesenchymal stem cells from bone marrow were exposed to mechanical pressure under additional estrogen treatment or estrogen receptor blockade. [Cells Tissues Organs] |
| POLICY NEWS | National Institutes of Health (United States) Food and Drug Administration (United States) Center for Biologics Evaluation and Research (United States) European Medicines Agency (European Union) Medicines and Healthcare Products Regulatory Agency (United Kingdom) Therapeutic Goods Administration (Australia) |
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