| PUBLICATIONS (Ranked by Impact Factor of the Journal) | Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Here, researchers identify adipose precursor cells within the skin and demonstrate that their dynamic regeneration parallels the activation of skin stem cells. [Cell] Abstract | Press Release The Effect of Synthetic Octacalcium Phosphate in a Collagen Scaffold on the Osteogenicity of Mesenchymal Stem Cells Results indicate that octacalcium phosphate crystals in a collagen matrix efficiently promote exogenously introduced osteogenic cells to initiate bone regeneration if the cells are pre-treated in a suitable differentiation condition. [Eur Cell Mater] Abstract Endurance Exercise Training Promotes Medullary Hematopoiesis The purpose of this study was to directly investigate the effects of endurance exercise training on hematopoiesis and to identify potential mechanisms responsible for any observed changes. [FASEB J] Abstract | Press Release Expression Patterns and Function of Chromatin Protein HMGB2 during Mesenchymal Stem Cell Differentiation This study addressed HMGB2 expression patterns in mesenchymal stem cells and its role during differentiation. [J Biol Chem] Abstract Human Dental Pulp Stem Cells Demonstrate Better Neural and Epithelial Stem Cell Properties than Bone Marrow-Derived Mesenchymal Stem Cells To understand the characteristics of dental pulp stem cells from impacted third molar, proliferation capacities, gene expression profiles, phenotypic, ultrastructural, and differentiation characteristics were analyzed in comparison with human bone marrow-derived mesenchymal stem cells, extensively. [Histochem Cell Biol] Abstract Expansion and Delivery of Adipose-Derived Mesenchymal Stem Cells on Three Microcarriers for Soft Tissue Regeneration Scientists compared the suitability of fabricated micronized acellular dermal matrix, micronized small intestinal submucosa, and gelatin microspheres as expansion and delivery scaffolds for adipose-derived mesenchymal stem cells. [Tissue Eng Part A] Abstract Human Mesenchymal Stem Cells Induced by Growth Differentiation Factor 5: An Improved Self-Assembly Tissue Engineering Method for Cartilage Repair In this study, researchers generated self-assembled constructs of human mesenchymal stem cells (hMSCs) using four different approaches: direct self-assembly of hMSCs with or without GDF-5, and predifferentiated hMSCs self-assembly with or without GDF-5. [Tissue Eng Part C Methods] Abstract Basement Membrane Collagen Type IV Expression by Human Mesenchymal Stem Cells during Adipogenic Differentiation Results suggest that upon mesenchymal stem cell-adipocyte differentiation collagen type IV synthesis and remodelling become necessary when intracellular accumulation of fat necessitates a dynamically supporting and instructive, partly denatured adipogenic pericellular type IV collagen scaffold. [J Cell Mol Med] Abstract Polybrene Inhibits Human Mesenchymal Stem Cell Proliferation during Lentiviral Transduction As presented here, exposure to polybrene alone at commonly used concentratons (1–8 µg/mL) negatively impacts human mesenchymal stem cell proliferation in a dose-dependent manner as measured by CyQUANT, EdU incorporation, and cell cycle analysis. [PLoS ONE] Abstract Electrospun Nanofiber-Based Regeneration of Cartilage Enhanced by Mesenchymal Stem Cells The objective of this study was to investigate the potential of poly(vinyl alcohol)/polycaprolactone (PVA/PCL) nanofiber scaffolds seeded with rabbit bone marrow-mesenchymal stem cell for cartilage tissue engineering in vitro and in vivo. [J Biomed Mater Res A] Abstract |
| SCIENCE NEWS | A Youthful Environment Can Rejuvenate Old Stem Cells Several recent studies have shown that the mechanical properties of the matrix in which mesenchymal stem cells are grown can affect the type of cell they turn into. So researchers reasoned that the cell’s microenvironment might also influence its regenerative potential. [Press release from New Scientist discussing research presented at the Strategies for Engineered Negligible Senescence meeting in Cambridge, United Kingdom] Press Release |
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