| TOP STORY | Mechanical Derivation of Functional Myotubes from Adipose-Derived Stem Cells Here, adipose-derived stem cells are shown to not just simply reflect the qualitative stiffness sensitivity of bone marrow-derived stem cells (BMSCs) but to exceed BMSC myogenic capacity, expressing the appropriate temporal sequence of muscle transcriptional regulators on muscle-mimicking extracellular matrix in a tension and focal adhesion-dependent manner. [Biomaterials] Abstract |
| PUBLICATIONS (Ranked by Impact Factor of the Journal) | Effects of Micropitted/Nanotubular Titania Topographies on Bone Mesenchymal Stem Cell Osteogenic Differentiation The effects of micropitted/nanotubular titania topographies on bone mesenchymal stem cell osteogenic differentiation was studied systematically by various microscopic and biological characterization techniques. [Biomaterials] Abstract Comparative Analysis of Paracrine Factor Expression in Human Adult Mesenchymal Stem Cells Derived from Bone Marrow, Adipose and Dermal Tissue Scientists evaluated paracrine factor expression patterns in mesenchymal stem cells isolated from adipose tissue, bone marrow and dermal tissues. [Stem Cells Dev] Abstract Nanomechanics of Human Adipose Derived Stem Cells: Small GTPases Impact Chondrogenic Differentiation The aim of this study was to investigate the impact of small GTPases on TGF-ß1 mediated chondrogenic differentiation of human adipose derived stem cells and compare it with BMP-2 induced hypertrophy, by assessing effects on intracellular and extracellular matrix. [Tissue Eng Part A] Abstract Evaluation of Bone Marrow-Derived MSC after Cryopreservation and Hypothermic Storage in Clinically Safe Medium Efficacy of cryopreservation of human bone marrow-derived mesenchymal stem cells (MSC) in clinically safe, animal product free medium containing 2, 5, and 10% DMSO was evaluated by measuring cell recovery, viability, apoptosis, proliferation rate, expression of a broad panel of MSC markers and osteogenic differentiation. [Tissue Eng Part C Methods] Abstract Mesenchymal Stromal Cells Primed with Paclitaxel Provide a New Approach for Cancer Therapy In this study, researchers hypothesized whether freshly isolated human bone marrow mesenchymal stem cells and mature murine stromal cells primed in vitro with anti-cancer drugs and then localized near cancer cells, could inhibit proliferation. [PLoS One] Abstract LPS-Pretreated Bone Marrow Stem Cells as Potential Treatment for Myocardial Infarction The purpose of this study was to investigate the distribution, the number, and the survival time of rat bone marrow mesenchymal stem cells, implanted in rats with myocardial infarction, that were initially pretreated with low dose of LPS. [Front Biosci] Abstract Human Adipose Tissue-Derived Mesenchymal Stem Cells Protect Kidneys from Cisplatin Nephrotoxicity in Rats Researchers tested whether human adipose tissue-derived mesenchymal stem cells can affect multiple target sites and protect against cisplatin-induced kidney damage. [Am J Physiol Renal Physiol] Abstract Rosuvastatin Elicits Kinase Insert Domain Receptor-Dependent Vasculogenic Response of Human Placental Stem Cells through PI3K/AKT Pathway Researchers assessed whether rosuvastatin may drive a gene program of vascular commitment and the secretion of trophic mediators with antiapoptotic, angiogenic and antifibrotic activities in human mesenchymal stem cells from full-term placentas. [Pharmacol Res] Abstract Spontaneous Transformation of Cynomolgus Mesenchymal Stem Cells In Vitro: Further Confirmation by Short Tandem Repeat Analysis In this study researchers provided evidence, using short tandem repeat analysis, that transformed mesenchymal stem cells are derived from cynomolgus mesenchymal stem cells. [Exp Cell Res] Abstract |
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