 | | Vol. 15.11 – 28 March, 2023 |
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| Researchers assessed diverse cell behaviors of bone mesenchymal stem cells on the β-tricalcium phosphate scaffolds with three representative pore morphologies.
[Bioactive Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Polycaprolactone/silk fibroin-aligned electrospun material was modified with ECM derived from human umbilical cord mesenchymal stem cells, and a dual-bionic nerve regeneration material was successfully fabricated.
[Bioactive Materials] |
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| Scientists showed that genistein, a predominant soy isoflavone, stimulated osteoblast differentiation of MSCs in vivo and in vitro. Female rats were subjected to bilateral ovariectomy; four weeks after surgery the rats were orally administered genistein for eight weeks.
[Acta Pharmacologica Sinica] |
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| A constructed aligned porous hydrogel scaffold carrying cells based on chitosan and oxidized chondroitin sulfate treated with a freeze-casting technique was fabricated, which aimed to induce the arrangement of periodontal tissue regeneration.
[ACS Biomaterials Science & Engineering] |
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| Scientists explored the neuroprotective potential of the secretome derived from neurotrophic factors-primed mesenchymal stromal cells using an endoplasmic reticulum stress-induced in vitro model system.
[Regenerative Medicine] |
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| The authors found that the expression of the splicing factor Y-box binding protein 1 (YBX1) in bone marrow stem cells (BMSCs) decreased with aging in mice and humans.
[EMBO Journal] |
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| Researchers showed that MSC-derived small extracellular vesicles specifically converted T helper 17 cells into IL-17 low-producer cells by degrading RAR-related orphan receptor RORγt at the protein level.
[Experimental & Molecular Medicine] |
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| Injection of human placental MSCs improved ovarian function and reproductive ability of premature ovarian insufficiency rats, compared to the sham and hormone groups.
[Journal of Ovarian Research] |
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| HUVECs were used to investigate the influences and mechanisms of human dental pulp stem cells (hDPSC)-exosomes on cell proliferation and migration. A rat model was established to verify the role of hDPSC-Exos in flap I/R injuries in vivo.
[Regenerative Medicine] |
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| Researchers studied the therapeutic potential of hypoxia-induced exosomal circular RNA OXNAD1 from human umbilical cord MSCs against spinal cord ischemia reperfusion.
[Biochemistry And Biophysics Reports] |
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| Investigators successfully fabricated polycaprolactone salt-leached scaffolds with two levels of a biomimetic calcium phosphate coating to examine their effects on mesenchymal stem cell osteogenesis.
[Cells Tissues Organs] |
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The authors discuss the main therapeutic uses of MSCs/DSCs, their mechanisms, extrinsic inflammatory cues and the intrinsic metabolic circuitries that govern the immunomodulatory functions of MSCs/DSCs.
[Cellular & Molecular Immunology] |
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| The American Urological Association and the Urology Care Foundation announced Dr. Ryan Flannigan as the latest recipient of the Rising Stars in Urology Research Award. Dr. Flannigan is an assistant professor in the Department of Urological Sciences at the University of British Columbia.
[The American Urological Association (Benzinga)] |
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| April 25 – 26, 2023
London, England, United Kingdom |
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| | Monash University – Melbourne, Australia |
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| | Umeå University – Umeå, Sweden |
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| | Delft University of Technology – Delft, Netherlands |
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| | InVitro Cell Research, LLC – Fort Lee, New Jersey, United States |
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| | National University of Singapore – Singapore, Singapore |
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