 | | Vol. 16.09 – 12 March, 2024 |
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| To improve the therapeutic efficiencies of MSCs in osteoarthritis treatment by carbonic anhydrase IX siRNA-based inflammation regulation and Kartogenin-based chondrogenic differentiation, the combination strategy of MSCs and the nanomedicine co-delivering KGN and siCA9 was used.
[ACS Nano] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Flow cytometric analysis, RNA sequencing, and differentiation ability were applied to detect the characteristics of stromal cells from 3D human brain organoids.
[Stem Cell Research & Therapy] |
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| Human adipose tissue-derived MSCs were co-cultured with bone marrow-derived monocyte/macrophage from DBA/1J or B6 mouse in the presence of osteoclastogenic condition.
[Tissue Engineering And Regenerative Medicine] |
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| Network pharmacology was used to predict the targets of BZBS in delaying senescence in MSCs. For in vitro studies, MSCs were treated with D-gal, BZBS, and NMN, and cell viability, cell senescence, stemness-related genes, and cell cycle were studied.
[Heliyon] |
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| The authors differentiated iPSCs into iPericytes of either the mesoderm or neural crest lineage using established protocols.
[Current Stem Cell Research & Therapy] |
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| Investigators found a positive feedback cross-talk between senescent tendon stem cells (s-TSCs) and macrophages. The conditioned medium from s-STCs could promote macrophage polarization mainly toward the M1 phenotype, whose CM reciprocally accelerated further s-TSC senescence.
[Small] |
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| The authors differentiated iPSCs into iPericytes of either the mesoderm or neural crest lineage using established protocols.
[Clinical Cancer Research] |
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| Researchers investigated the anti-fibrogenic properties and mechanisms of the conditioned medium from human umbilical cord/placenta-derived MSCs in a murine intestinal fibrosis model and human primary intestinal myofibroblasts.
[Stem Cell Research & Therapy] |
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| Investigators describe characteristics and isolation methods of MSC-extracellular vesicles, and focus on their therapeutic potential describing its roles in tissue repair, anti-fibrosis, and cancer with an emphasis on the molecular mechanism and immune modulation and clinical trials.
[Life Sciences] |
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| Cellcolabs has raised $8.7 million from angel investors to expand production facilities and grow employee headcount. The Sweden-based company manufactures specialized stem cells that can be used to develop cell therapy treatments for diseases associated with inflammation.
[Sifted] |
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| April 22 – 25, 2024
Baltimore, Maryland, United States |
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| | University of California, Davis – Sacramento, California, United States |
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| | King’s College London – London, England, United Kingdom |
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| | University of Sydney – Sydney, Australia |
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| | UC Davis – Davis, California, United States |
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| | BC Provincial Health Services Authority – Vancouver, British Columbia, Canada |
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