 | | Vol. 5.29 – 17 August, 2020 |
| |
|
|
| The authors developed a microfluidic chip formed by Hutchinson-Gilford Progeria Syndrome-smooth muscle cells generated from induced pluripotent stem cells, to study their vulnerability to flow shear stress.
[Nature Communications] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Researchers used primate pluripotent stem-cell-derived cardiomyocytes that mimicked fetal cardiomyocytes in vitro to discover hundreds of endogenous retrovirus transcripts from the primate-specific MER41 family.
[Developmental Cell] |
|
|
|
| Contractions of differentiated cardiomyocytes were observed in 2D cultures after two weeks and in 3D cultures after four weeks.
[Materials Science and Engineering: C] |
|
|
|
| Investigators demonstrated the production of cardiomyocytes by using high definition direct writing technologies to influence embryoid bodies aggregation from stem cells.
[Bioprinting] |
|
|
|
| In cardiomyocytes, isoproterenol treatment markedly increased reactive oxygen species and inhibited autophagy, which were greatly alleviated by pretreatment with baicalein.
[Acta Pharmacologica Sinica] |
|
|
|
| Researchers focused on using Wnt inhibitors to study the differentiation of human iPSC-cardiac progenitor cells under 2D or 3D culture conditions.
[Scientific Reports] |
| |
|
|
| Skeletal muscle-specific CIP was localized to the centrosome in myoblasts and relocated to the outer nuclear envelope in myotubes upon differentiation.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
| Scientists showed that C2C12 myoblasts spontaneously organized into highly aligned myotube tissues on the mm to cm scale, when cultured on sufficiently soft yet fully isotropic gelatin hydrogel substrates.
[Scientific Reports] |
| |
|
|
| The two-layer tissue scaffolds were printed in a stomach model. Gelatin-alginate hydrogels with human gastric epithelial cells and human gastric smooth muscle cells were used as bioinks to mimic the anatomical structure of a stomach.
[Biofabrication] |
|
|
|
| Researchers report that the microRNA miR‐134‐5p potentiated inorganic phosphate‐induced calcium deposition in vascular smooth muscle cells by inhibiting histone deacetylase 5.
[Journal of Cellular and Molecular Medicine] |
|
|
|
| Scientists showed that the binding of deglycosylated-azithromycin to transgelin enhanced the contractility of intestinal smooth muscle cells by facilitating the assembly of actin filaments into tight bundles and stress fibers.
[iScience] |
|
|
|
|
| The authors provide a comprehensive review of the cardiac effects of physical activity, beginning with a brief history of exercise in cardiovascular medicine and then discussing seminal work on the physiological effects of exercise in healthy, diseased and aged hearts.
[Nature Metabolism] |
|
|
|
|
| Scholar Rock, Inc. announced that the FDA has granted Rare Pediatric Disease designation for SRK-015 for the treatment of Spinal Muscular Atrophy, a progressive, rare genetic disease that leads to motor function impairments.
[Scholar Rock, Inc.] |
|
|
|
|
| November 2 – November 3
Virtual |
|
|
|
|
|
| | Novo Nordisk A/S – Måløv, Denmark |
|
|
|
| | Albert Einstein College of Medicine – New York, New York, United States |
|
|
|
| | UPMC Children’s Hospital of Pittsburgh – Pittsburgh, Pennsylvania, United States |
|
|
|
| | Albert Einstein College of Medicine – New York, New York, United States |
|
|
|
| | Duke University – Durham, North Carolina, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
