 | | Vol. 6.09 – 15 March, 2021 |
| |
|
|
| Scientists found that the microtubule motor Kinesin-1 distributed mRNAs and ribosomes along microtubule tracks to discrete domains within the cardiomyocyte.
[Nature Communications] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| SENP2 deficiency promoted P7 and adult cardiomyocyte dedifferentiation and proliferation both in vitro and in vivo.
[Clinical Science] |
|
|
|
| Mixed populations of cardiosphere-derived stem and progenitor cells containing proliferative and cardiomyogenically committed cells were obtained from adult rat hearts.
[Integrative Biology] |
| |
|
|
| Scientists present a roadmap for the origin and diversity of major cell categories and found that muscle and neuron cells were conserved cell types.
[Cell Reports] |
|
|
|
| The effect of cigarette smoke extract on RANKL/RANK expression and that of exogenous RANKL on ubiquitin-proteasome pathway in C2C12 myotubes were investigated in vitro.
[American Journal of Respiratory Cell and Molecular Biology] |
|
|
|
| To further understand transcriptional regulation by DUX4, scientists performed nanopore long-read direct RNA sequencing of human muscle cells induced by DUX4.
[Human Molecular Genetics] |
| |
|
|
| The therapeutic potential of Ophiocordyceps sinensis for pulmonary hypertension (PH) was investigated using rodent PH models, and cultured pulmonary artery endothelial and smooth muscle cells, with a focus on the involvement of TRPM7.
[Translational Research] |
|
|
|
| ANGPTL8 shRNA and ANGPL8 overexpression were used in aortic vascular smooth muscle cells to investigate the mechanism of ANGPTL8 in chronic intermittent hypoxia.
[Biochemical Pharmacology] |
|
|
|
| Researchers investigated the effect of thalidomide on cellular functions of prostate stromal cells and human prostate smooth muscle contraction.
[Prostate] |
|
|
|
| HOXA cluster antisense RNA 3 and phosphodiesterase 5A were upregulated in human pulmonary artery smooth muscle cells in the presence of hypoxia, while miR-675-3p was downregulated.
[Biochemical Genetics] |
|
|
|
| Investigators report that PKM2 deletion in SMC reduced injury-induced neointimal hyperplasia by inhibiting SMC proliferation and migration, suppressing synthetic phenotype, and reducing aerobic glycolysis associated with decreased extracellular signal-regulated kinase, mTOR, and signal transducer and activator of transcription 3 signaling.
[Arteriosclerosis, Thrombosis, and Vascular Biology] |
|
|
|
|
| The authors summarize signaling networks that govern in vivo cell fate decisions and in vitro derivation of distinct vascular smooth muscle cell (VSMC) progenitors, as well as key regulators that terminally specify lineage-specific VSMCs.
[Circulation Research] |
|
|
|
|
| The National Heart, Lung, and Blood Institute recently awarded Jonathan H. Jaggar, PhD, Maury Bronstein Endowed Professor in the Department of Physiology at the University of Tennessee Health Science Center a $2.3 million grant for his study titled “PKD proteins in endothelial cells.” The proposal’s goal is to provide a new understanding of how endothelial cells regulate blood pressure.
[University of Tennessee] |
|
|
|
|
|
|
|
| | Mount Sinai Health System – New York, New York, United States |
|
|
|
| | University of Southern Denmark – Odense M, Denmark |
|
|
|
| | Albert Einstein College of Medicine – Bronx, New York, United States |
|
|
|
| | The University of Utah School of Medicine – Salt Lake City, Utah, United States |
|
|
|
| | University of Alabama at Birmingham – Birmingham, Alabama, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
