 | | Vol. 6.41 – 29 November, 2021 |
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| Investigators investigated the contributions of chromatin regulatory complexes to fusion positive rhabdomyosarcoma (FP-RMS) tumor maintenance. They defined the mSWI/SNF functional repertoire in FP-RMS.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists showed that rescue of pyrimidine biosynthesis by administration of uridine or by genetic targeting of ENPP1/AMP pathway enhanced repair after cardiac injury.
[Journal of Clinical Investigation] |
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| Researchers identified the potential roles of glycogen synthase kinase-3β (GSK-3β), a critical regulator of cell proliferation and differentiation, in cardiac progenitor cell proliferation post-myocardial infarction.
[Journal of Cellular Physiology] |
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| The authors explored the role and molecular mechanism of long non-coding RNA small nucleolar RNA host gene 1 (SNHG1) in ischemic cardiomyocyte injury.
[Molecular Medicine Reports] |
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| Researchers elaborated on a bi-phasic effect of gelatin in skeletal muscle regeneration, mediated by hormetic effects of reactive oxygen species.
[Disease Models & Mechanisms] |
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| The authors clarified the role of nitric oxide (NO) in myoblast proliferation, migration and differentiation. Baseline NO levels were established in vitro, whereafter NO levels were manipulated during myogenesis using L-NAME or SIN-1.
[Biochimie] |
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| Using a comprehensive combination of genetically modified fish, electrophysiology, and gene expression analysis, scientists demonstrated that zebra fish cardiac myocytes and vascular smooth muscle expressed functional ATP-sensitive potassium channels channels of similar subunit composition, structure, and metabolic sensitivity to their mammalian counterparts.
[Journal of Physiology] |
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| Scientists investigated the changes in large-conductance Ca2+-activated K+ channels from human umbilical arterial smooth muscle cells experiencing gestational diabetes mellitus.
[Life Sciences] |
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| Investigators investigated the role of runt-related transcription factor 3 (RUNX3) in extracellular matrix remodeling and vascular smooth muscle cell function, and further explored the underlying mechanism.
[Journal of Molecular Histology] |
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| The authors discuss the current understanding of the molecular processes that contribute to the functional failure of satellite cells during aging.
[Ageing Research Reviews] |
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| Scientists provide a comparative review of recent advances in artificial muscle based on various operating mechanisms.
[Microsystems & Nanoengineering] |
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| Neurana Pharmaceuticals, announced it has completed enrollment of its 1,000 patient Phase III RESUME-1 study of tolperisone for the relief of muscle spasm associated with acute, painful musculoskeletal conditions.
[Neurana Pharmaceuticals. Inc.] |
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| March 9 – 11, 2022
Melbourne, Victoria, Australia |
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| University of California, Los Angeles – Los Angeles, California, United States |
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| Sarepta Therapeutics Inc. – Columbus, Ohio, United States |
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| Nestl̩ S.A. РLausanne, Switzerland |
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| The Victor Chang Cardiac Research Institute – Darlinghurst, Australia |
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| | Saint Louis University – St. Louis, Missouri, United States |
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