 | | Vol. 7.03 – 31 January, 2022 |
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| Scientists showed defective mechano-phenotype signatures of vascular smooth muscle cells in abdominal aortic aneurysms measured with ultrasound tweezers-based micromechanical system and single-cell RNA sequencing technique.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| After myocardial ischemia reperfusion surgery, IL-1R2 expression was significantly increased in heart of wild-type mice.
[Cell Death & Disease] |
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| Scientists showed that norepinephrine secretion from intrinsic cardiac adrenergic cells was increased through activation of Toll-like receptor 4 to aggravate myocardial TNF-α production and dysfunction by lipopolysaccharide.
[Communications Biology] |
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| Septic rats were modeled by cecal ligation puncture while in vitro septic cardiomyocyte H9C2 were induced by lipopolysaccharide.
[Cell Death Discovery] |
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| Gene expressions of XR_596701 and miR-344b-5p were detected by quantitative real-time PCR in intermittent hypoxia-induced H9c2 cells.
[Cell Death Discovery] |
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| Researchers explored the effects of interventions with the trypanosomicidal drug benznidazole alone or combined with pentoxifylline, a methylxanthine derivative shown to modulate immunological and cardiac abnormalities in a model of chronic chagasic cardiomyopathy, on parasite load and expression of miR-145-5p and miR-146b-5p.
[Scientific Reports] |
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| An in vitro cell model was established, followed by a comprehensive evaluation of cell viability and pyroptosis. The binding relationships of miR-378a-3p and ELAVL1, HuR, and NLR family pyrin domain containing 3 were analyzed.
[Hypertension Research] |
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| In vitro and in vivo experiments showed that the expression of adiponectin was decreased and the expression of Il6 and Tnf was increased in the nerve-crushed group compared to that in the control group.
[Scientific Reports] |
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| Scientists reported here that in response to mitochondrial reactive oxygen species, murine muscle stem cells (MuScs) directly fused with neighboring myofibers; this phenomenon removed electron transport chain-dysfunctional MuSCs from the stem cell compartment.
[Nature Aging] |
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| The authors investigated the specific involvement of apoptosis-inducing factor, a mitochondrial oxidoreductase in regulating mitochondrial energy metabolism and mitophagy in pulmonary artery smooth muscle cells.
[Cell & Bioscience] |
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| Researchers investigated the capacity for thrombin to trigger inflammation and induce cell proliferation in vascular smooth muscle cells.
[Biomed Research International] |
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| Scientists discuss the advantages and limitations of 2D human pluripotent stem cell (hPSC)-cardiomyocyte system, and introduce the recent development of three-dimensional culture platforms derived from hPSCs.
[Ebiomedicine] |
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| Capricor Therapeutics announced that it has entered into a partnership with Nippon Shinyaku Co., Ltd. for the exclusive commercialization and distribution in the United States of Capricor’s lead asset, CAP-1002, for the treatment of Duchenne muscular dystrophy, a rare neuromuscular disease with limited treatment options.
[Capricor Therapeutics] |
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| Helmholtz Centre for Infection Research – Braunschweig, Germany |
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| Ksilink – Strasbourg, France |
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| Ume̴ University РUme̴, Sweden |
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| Fox Chase Cancer Center, Temple University – Philadelphia, Pennsylvania, United States |
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| RWTH Aachen Medical School – Aachen, Germany |
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