Muscle Cell News Volume 7.25 | Jul 18 2022

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    2022-07-18 | MUSCN 7.25


    Muscle Cell News by STEMCELL Technologies
    Vol. 7.25 – 18 July, 2022
    TOP STORY

    GLI3 Regulates Muscle Stem Cell Entry Into GAlert and Self-Renewal

    Researchers found that GLI3 processing by the primary cilium played a critical role for satellite cell function.
    [Nature Communications]

    Full ArticlePress Release
    Survey results on the needs and challenges in the human pluripotent stem cell field
    PUBLICATIONSRanked by the impact factor of the journal

    Cardiac-Specific Overexpression of Ndufs1 Ameliorates Cardiac Dysfunction After Myocardial Infarction by Alleviating Mitochondrial Dysfunction and Apoptosis

    Investigators showed that NADH:ubiquinone oxidoreductase core subunit S1 (Ndufs1) expression was decreased in the hearts of heart failure patients and mice with myocardial infarction.
    [Experimental and Molecular Medicine]

    Full Article

    HDAC11 Regulates the Proliferation of Bovine Muscle Stem Cells through the Notch Signaling Pathway and Inhibits Muscle Regeneration

    The authors determined the role of histone deacetylase 11 (HDAC11) in the proliferation and differentiation of bovine muscle stem cells.
    [Journal of Agricultural and Food Chemistry]

    AbstractGraphical Abstract

    MOTS-C Promotes Muscle Differentiation In Vitro

    Scientists investigated the role of mitochondrial open reading frame of the 12 S rRNA-c (MOTS-c) in the differentiation of human and murine muscle progenitor cells.
    [Peptides]

    AbstractGraphical Abstract

    Methylglyoxal Enhances the Proliferation of Vascular Smooth Muscle Cells via Akt Phosphorylation

    Researchers inspected the proliferative capacity of methylglyoxal in vascular smooth muscle cells, which had a crucial role in atherosclerosis and restenosis.
    [Journal of Receptors and Signal Transduction]

    Abstract

    Synergistic Effect of VEGF and SDF-1α in Endothelial Progenitor Cells and Vascular Smooth Muscle Cells

    Endothelial progenitor cells were isolated from rat bone marrow and their morphology and function were studied.
    [Frontiers in Pharmacology]

    Full Article

    Shexiang Baoxin Pill Regulates Intimal Hyperplasia, Migration, and Apoptosis after Platelet-Derived Growth Factor-BB-Stimulation of Vascular Smooth Muscle Cells via miR-451

    Scientists investigated the regulatory roles of Shexiang Baoxin Pill in neointimal formation and vascular smooth muscle cells (VSMCs) invasion and apoptosis, as well as the potential molecular mechanisms using cultured VSMCs model of vascular injury in vitro.
    [Chinese Journal of Integrative Medicine]

    Abstract
    Request your free copy of the 'Directed Differentiation of Pluripotent Stem Cells' Wallchart
    REVIEWS

    Cardiovascular Protection by SGLT2 Inhibitors – Do Anti-Inflammatory Mechanisms Play a Role?

    Investigators summarize the current knowledge on the anti-inflammatory effects of sodium glucose co-transporter 2 (SGLT2) inhibitors as one of the mechanisms potentially mediating their cardiovascular benefits.
    [Molecular Metabolism]

    AbstractFull Article
    INDUSTRY AND POLICY NEWS

    Seelos Therapeutics Doses First Patient in an Open Label Basket Study of SLS-005 in Amyotrophic Lateral Sclerosis in Australia and Provides an Enrollment Update of its Study on the HEALEY ALS Platform

    Seelos Therapeutics, Inc. announced dosing of the first patient in an open-label basket study of SLS-005 for the treatment of patients with amyotrophic lateral sclerosis (ALS) in Australia.
    [Seelos Therapeutics, Inc.]

    Press Release
    FEATURED EVENT

    The Australasian Society for Stem Cell Research (ASSCR) Annual Meeting

    November 16 – 18, 2022
    Melbourne, Victoria, Australia

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Research Fellow – Muscle Biology

    Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio, United States

    Histologist – Muscle & Nerve Tissue

    Sarepta Therapeutics, Inc. – Columbus, Ohio, United States

    Research Associate – Cardiovascular Research

    King’s College London – London, England, United Kingdom

    Associate Professor – Thematic Research Programs

    The Chinese University of Hong Kong – Hong Kong, China

    Research Fellow – Structural Heart Biomechanics

    National University of Ireland Galway – Galway, Ireland

    > See All Jobs

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