| Vol. 8.08 – 13 March, 2023 |
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| Researchers identified a Tbx5-expressing ventricular cardiomyocyte-like precursor population, in the injured adult mammalian heart. [NPJ Regenerative Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Using in vivo and in vitro approaches, investigators identified the lncRNA Malat1 as a key player in postnatal cardiac regeneration. [JCI Insight] |
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| Scientists investigated if Secreted Frizzled Related Protein 2 (Sfrp2) would drive differentiation of human induced pluripotent stem cells into cardiomyocytes, and found that Sfrp2 induced robust cardiac differentiation. [Scientific Reports] |
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| Stable biohybrid designs of centimeter-scale skeletal muscle tissue were realized via extrusion-based bioprinting of an optimized polymeric blend based on gelatin methacryloyl and sodium alginate. [Advanced Healthcare Materials] |
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| The authors investigated the previously uncharacterized regulatory roles of YTHDC1, a N(6)-methyladenosine (m6A) reader in mouse satellite cells. [eLife] |
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| Researchers investigated mechanisms of age-related changes in myogenic progenitor cells using the tissue-specific microRNA 501. [Molecular Metabolism] |
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| Scientists found the canonical Wnt pathway to be activated in mesenchymal progenitors from cancer-induced cachectic mouse muscle and then induced β-catenin transcriptional activity in murine mesenchymal progenitors. [Developmental Cell] |
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| Investigators combined in vitro experiments and physical modeling to show that three-dimensional clusters initiated when cellular contractile forces induced a hole in a flat smooth muscle cell sheet. [Communications Biology] |
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| The authors critically compare muscle tissue engineering for biomedical versus food applications, and discuss the limitations of biomedical tissue engineering practices in achieving the important requirements of food production. [Trends In Biotechnology] |
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| Scientists summarize the latest progress from studies on regulated cell death pathways in cardiomyocytes in the context of the pathogenesis of cardiomyopathies, with particular emphasis on apoptosis, necroptosis, ferroptosis, autophagy, and pyroptosis. [Acta Pharmacologica Sinica] |
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| Muscular Dystrophy Association announced two research grants designed to address potential transgene-triggered safety concerns in Duchenne muscular dystrophy gene therapies. [Muscular Dystrophy Association] |
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| April 20 – 21, 2023 Sheffield, England, United Kingdom |
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| Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| Hannover Medical School – Hanover, Germany |
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| Yale School of Medicine – New Haven, Connecticut, United States |
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| University of Minnesota – Minneapolis, Minnesota, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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