 | | Vol. 8.28 – 21 August, 2023 |
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| The authors investigated whether the endoplasmic reticulum stress signaling pathway initiated by the turbulence of mitochondrial fusion and fission under stressful circumstances was involved in cardiomyocyte damage.
[Journal Of Cellular And Molecular Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| To elucidate the effects of progerin in cardiomyocytes, scientists first obtained skin fibroblasts from a de-identified Hutchinson-Gilford progeria syndrome patient and both parents from the Progeria Research Foundation.
[Cell and Tissue Research] |
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| The rat cardiomyocyte H9C2 cell line was exposed to hypoxia/reoxygenation and the roles of miR-21 and HIPK3 in regulating cell viability and apoptosis were evaluated by cell counting kit-8 assay, terminal-deoxynucleotidyl-transferase -mediated dUTP nick end labeling, and flow cytometry.
[Bioscience Reports] |
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| Using in vitro experiments, researchers transfected miR-29c mimic and antagomir into HL-1 cells to explore the effect of miR-29c on inflammation in hyperglycemic conditions.
[Molecular and Cellular Biochemistry] |
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| Investigators reported that AP-1 family member activating transcription factor 3 (ATF3) prevented satellite cell (SC) premature activation. Atf3 was rapidly and transiently induced in SCs upon activation.
[Nature Communications] |
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| Scientists utilized pericyte (PC)-fused myofibers using PC-specific lineage tracing mouse to observe whether muscle resident PCs had myogenic potential during daily life.
[Stem Cell Research & Therapy] |
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| Phosphoproteomic analyses of the tibialis anterior muscle after contraction in two mouse models of estrogen deficiency, ovariectomy (Ovx/Sham), and natural aging-induced ovarian senescence OA/YA, identified a total of 2,593 and 3,507 phosphopeptides in Ovx/Sham and OA/YA datasets, respectively.
[Aging-Us] |
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| The authors investigated the effects of different levels of autophagy induced by transient serum starvation on the metabolism, lipid metabolism, and differentiation of porcine skeletal muscle satellite cells.
[Scientific Reports] |
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| Researchers investigated the contribution of circRNAs to abdominal aortic aneurysm (AAA) pathogenesis and their potential application to improve AAA diagnostics.
[Molecular Therapy-Nucleic Acids] |
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| Scientists developed a stretchable electrochemical sensor by electrospinning aligned and elastic polyurethane nanofibers on the surface of PDMS film and further modification of conductive polymer PEDOT:PSS-LiTFSI-CoPc on the nanofibers.
[ACS Sensors] |
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| Investigators explored the role of LINC02015 in the cell proliferation and apoptosis of vascular smooth muscle cells to explain the pathogenesis of aortic diseases.
[Cell Death Discovery] |
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| Adventitial fibroblasts (AFs) and vascular smooth muscle cells were obtained from aorta of the Wistar-Kyoto rat and spontaneously hypertensive rat. Extracellular vesicles were separated from AFs culture with the ultracentrifugation method.
[Life Sciences] |
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| The authors provide an overview of the diverse array of vertebrates that have been studied for their cardiac regenerative potential and discuss differential heart regeneration outcomes in closely related species.
[Nature Reviews Cardiology] |
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| Scientists discuss emerging pathways that regulate muscle atrophy, including oncostatin M, and ectodysplasin A2 receptor signaling, outcomes of recent clinical trials, and potential drug targets for future therapies.
[Trends in Pharmacological Sciences] |
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| The National Institutes of Health (NIH) awarded a little more than $2.5 million to researchers at the University of Arkansas to study how exercise can mitigate the decline of tissue function with aging.
[University of Arkansas] |
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| October 16 – 19, 2023
Hong Kong |
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| | University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| | Creative Biolabs – New York, New York, United States |
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| | Center for Excellence in Molecular Cell Science – Shanghai, China |
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| | University of Florida – Gainesville, Florida, United States |
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| | IRB Barcelona – Barcelona, Spain |
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