 | | Vol. 9.07 – 4 March, 2024 |
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| Researchers reported enhanced efficacy of our miR reprogramming cocktail miR combo, miR-1, miR-133a, miR-208a, and miR-499, via RNA-sensing receptor stimulation.
[Molecular Therapy – Nucleic Acids] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors employed a genome-wide CRISPR screen in a human induced pluripotent stem cell to cardiomyocyte (CM) differentiation system and revealed that BRD4 regulated CM differentiation.
[Nature Cardiovascular Research] |
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| By combining 3D-tissue-engineered-skeletal muscles and shRNA technologies, researchers developed a disease modelling strategy to induce distinct genetic deficiencies in a single human induced pluripotent stem cell-derived myogenic progenitor cell line within one week.
[Skeletal Muscle] |
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| Eight overweight but otherwise healthy sedentary adults were studied before and 14, 28, and 56 days after initiating atorvastatin therapy.
[JCI Insight] |
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| Investigators elucidated the role of circ_0004872 and the potential mechanism in atherosclerosis. The level of circ_0004872, miR-424-5p, and fibroblast growth factor receptor substrate 2 (FRS2) was detected using qRT-PCR.
[Molecular And Cellular Biochemistry] |
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| Scientists presented data that established a novel interaction between aquaporin-1 and the proteolytic enzyme caspase-3.
[American Journal Of Physiology-Lung Cellular And Molecular Physiology] |
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| Researchers determined the acetylated state of the microtubule network in the mesenteric arteries of spontaneously hypertensive rats.
[Biochemical Journal] |
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| The authors describe the molecular, preclinical, and clinical evidence supporting the efficacy of histone deacetylase (HDAC) inhibitors in countering disease progression by targeting pathogenic networks of gene expression in multiple muscle-resident cell types of patients with Duchenne muscular dystrophy.
[Trends in Molecular Medicine] |
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| The Chan Zuckerberg Initiative today announced a $4 million grant to support research led by the UCLA Samueli School of Engineering that will examine cellular behaviors, many of which play a key role in developing immunity to pathogens and disease.
[UCLA Samueli School of Engineering] |
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| March 21 – 23, 2024
Tokyo, Japan |
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| | Pennington Biomedical Research Center – Baton Rouge, Louisiana, United States |
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| | University of Southern California – Los Angeles, California, United States |
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| | Johns Hopkins Medicine Pathology – Baltimore, Maryland, United States |
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| | UC Davis – Davis, California, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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